DTP Methoxyflurane

Question 1

Methoxyflurane drug class

Answer 1

Analgesic ( at low doses )

Question 2

Pharmacology of methoxyflurane

Answer 2

Inhalation agent that provides analgesia at low doses.
More susceptible to metabolism than other halogenated ethers
Greater propensity to diffuse into fatty tissue.

Question 3

Metabolism of methoxyflurane

Answer 3

By the liver and excreted mainly by the lungs

Question 4

Indications for methoxyflurane

Answer 4

Pain

Question 5

Contraindications for methoxyflurane

Answer 5

1. KSAR
2. Hx of malignant hyperthermia
3. Hx of signicant liver or renal disease
4. t monitor pain level and self administration

Question 6

Precautions for methoxyflurane

Answer 6

1. ALOC

2. Intoxicated or drug affected patients

Question 7

Side effects of methoxyflurane

Answer 7

1. Cough
2. ALOC
3. Hepatic or renal failure following repeated high doses

Question 8

Presentation of methoxyflurane

Answer 8

3ml glass bottle

Question 9

Duration of methoxyflurane

Answer 9

5-10mins

Question 9

Schedule of methoxyflurane

Answer 9

S4 restricted drug

Question 10

Onset of methoxyflurane

Answer 10

1-3mins

Question 12

Doses of methoxyflurane for adults

Answer 12

3ml repeatable after 20 mins, max dose 6ml

Question 13

Dose for Paediatrics

Answer 13

3 ml non repeatable

Question 14

Special notes for methoxyflurane

Answer 14

1. Deep sedation in pts < 5 yrs old
2. At no time should unconsciousness be deliberately induced by administration
3. At no time should a pt self administering be left unattended.
4. The lowest dose should be used to achieve analgesia
5. If the pt prefers simultaneous administration through nose and mouth a face mask can be connected prior to administration
6. Total weekly dose should not exceed 15 mls
7. Only 1 in the back of the vehicle, 2 per shift per officer