Drugs we love

Question 1

Describe the Vaughan Williams system for classifying drugs

Answer 1

It classifies antidysrythmic drugs

Class 1 - sodium channel blockers
Class 1 has 3 subclasses, a b and c that categorise the effect on the action potential.
Class 2 - beta blockers
Class 3 - potassium channel blockers
Class 4 - calcium channel blockers
Unclassified - adenosine and digoxin as ex.

Question 2

Name some loop diuretics

Answer 2

Furosemide
Bumetanide
- ide

Question 3

Name some ACE inhibitors

Answer 3

ramipril
lisinopril
(pril)

Question 4

Name some angiotensin-II receptor blockers

Answer 4

Candesartan
losartan
(sartan)

Question 5

Name some aldosterone receptor antagonists

Answer 5

spironolactone

Question 6

Name some beta blockers

Answer 6

bisoprolol
atenolol
(lol suffix)

Question 7

Name some calcium channel blockers

Answer 7

2 types:
Dihydropyradine derivatives:
amlodipine
lercanidine

Rate limiting:
verapamil
diltiazem

Question 8

Name some nitrates

Answer 8

Glyceryl trinitrate

isosorbide dinitrate with hydralazine

Question 9

Name a K+ channel inhibitor

Answer 9

nicorandil

Question 10

Name a “f” type channel inhibitor

Answer 10

ivabradine

Question 11

Name a unique anti anginal

Answer 11

ranolazine