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HOSA Pharmacology simplified > Drugs that affect the GI System > Flashcards

Drugs that affect the GI System Flashcards

1
Q

antacids uses

A

treatment of hyperacidity caused by heartburn, indigestion, GERD, peptic ulcer

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2
Q

aluminum antacids SE

A

constipation, intestinal impaction, anorexia, weakness, tremors, bone pain

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3
Q

magnesium antacids SE

A

diarrhea, dehydration, high magnesium

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4
Q

calcium antacids SE

A

rebound acid, alkalosis, hypercalcemia, confusion, headache, renal calculi, neurologic issues

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5
Q

sodium bicarbonate antacids SE

A

alkalosis, rebound acid

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6
Q

antacids CI

A

abdominal pain, lact

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7
Q

sodium bicarbonate antacids CI

A

CV issues

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8
Q

calcium antacids CI

A

renal calculi, hypercalcemia

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9
Q

aluminum antacids precautions

A

gastric outlet obstruction, upper GI bleeding

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10
Q

calcium antacids precaution

A

respiratory insufficiency, heart disease

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11
Q

antacids interact

A

digoxin, isoniazid, phenytoin, chlorpromazine, tetracycline, corticosteroids, salicylates

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12
Q

H2 Antagonists uses

A

heartburn, indigestion, sour stomach, GERD, gastric/duodenal ulcer, excessive gastric secretions

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13
Q

h2 antagonists SE

A

dizzy, somnolence, headache, confusion, hallucination, diarrhea

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14
Q

H2 antagonists precautions

A

severely ill, elderly, debilitated, diabetes, preg/lact

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15
Q

H2 antagonists interact

A

antacids, metoclopramide, carmustine, opioids, anticoag, digoxin

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16
Q

H2 antagonists ex

A

cimetidine, famotidine, nizatidine, ranitidine

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17
Q

PPIs uses

A

gastric and duodenal ulcers with h. pylori, GERD, erosive esophagitis, hypersecretory, bleeding prevention with antiplatelets

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18
Q

PPIs SE

A

headache, abdominal pain

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19
Q

PPIs CI

A

preg/lact

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20
Q

PPIs precautions

A

elderly

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21
Q

PPIs interact

A

sucralfate, ketoconazole, ampicillin, anticoagulants, digoxin, benzodiazepines, phenytoin, clarithromycin, bisphosphonates

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22
Q

PPIs ex

A

dexlansoprazole, esomeprazole, lansoprazole, omeprazole, pantoprazole, rabeprazole

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23
Q

GI stimulants MOA

A

increase motility of upper GI tract

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24
Q

GI stimulants uses

A

GERD, gastric stasis

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25
GI stimulants SE
usually mild SE: restless, drowsy, dizzy, tremor, involuntary movement, muscle rigidity, grimacing, depression
26
GI stimulants CI
GI obstruction, gastric perforation/hemorrhage, pheochromocytoma, parkinsons, seizures
27
GI stimulants precautions
diabetes, CV disease, preg/lact
28
GI stimulants interact
cholinergic blockers, opioids, digoxin, MAOIs, levodopa
29
GI stimulants ex
metoclopramide
30
antiemetics uses
preventatively for: pre/post surgery, with antineoplastics, with radiation therapy, during pregnancy
31
antiemetics SE
drowsy
32
antiemetics CI
severe CNS depression, heart block, prolonged QT, preg, young children
33
antiemetics precautions
glaucoma, obstructive GI or genitourinary disease, older men
34
antiemetics interact
CNS depressants, antihistamines, anatacids, rifamin, lithium
35
antiemetics ex
chlorpromazine, perphenazine, prochlorperazine, promethazine, trimethobenzamide, dolasetron, granisetron, ondansetron, palonosetron, dronabinol, nabilone
36
misc acid reducers ex
sucralfate, misoprostol
37
aminosalicylates uses
chron disease, ulcerative colitis
38
aminosalicylates SE
abdominal pain, headache, dizzy, fever
39
aminosalicylates CI
sulfa allergy, intestinal obstruction, less than 2
40
aminosalicylates precautions
preg/lact
41
aminosalicylates interact
digoxin, methotrexate, hypoglycemics, warfarin
42
aminosalicylates ex
balsalazide, mesalamine, olsalazine, sulfasalazine
43
antidiarrheals uses
diarrhea
44
antidiarrheals SE
anorexia, constipation, abdominal pain, dizzy, drowsy, headache, sedation, euphoria, rash
45
antidiarrheals CI
diarrhea with bacteria that can harm intestinal mucosa, pseudomembranous colitis
46
antidiarrheals precautions
preg/lact
47
antidiarrheals interact
antihistamines, opioids, sedatives, hypnotics, antidepressants
48
antidiarrheals ex
bismuth, crofelemer, loperamide
49
antiflatulents uses
relieve excessive gas caused by: postop, dyspepsia, peptic ulcer, IBS, diverticulosis
50
antiflatulents SE
none
51
antiflatulents precautions
preg/lact
52
antiflatulents interact
can decrease effectiveness of other drugs
53
antiflatulents ex
simethicone, charcoal
54
stimulant, emollient, and saline laxatives use
evacuate colon for exams
55
stool softeners uses
strain prevention
56
psyllium and polycarbophil use
IBS, diverticulosis
57
hyperosmotic laxatives use
decrease blood ammonia levels with hepatic encephalopathy
58
laxatives SE
constipation, diarrhea, water and electrolyte loss, abdominal pain, perianal irritation, fainting, bloating, flatulence, weakness
59
laxatives CI
lots of abdominal pain, vomiting, signs of acute appendicitis, fecal impaction, intestinal obstruction, acute hepatitis
60
laxatives precautions
rectal bleeding, preg/lact
61
laxatives interact
vitamin KADE, milk, antacids, H2 antagonists
62
stimulant laxatives ex
cascara sagrada, sennosides, bisacodyl
63
hyperosmotic laxatives ex
glycerine, lactulose, lubiprostone
64
stool softeners ex
docusate

HOSA Pharmacology simplified (6 decks)

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