Analgesics Flashcards

1
Q

Salicylates Ex

A

Aspirin, magnesium salicylate, diflunisal

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2
Q

Salicylates MOA

A

inhibit prostaglandins

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3
Q

Salicylates uses

A

mild-mod pain, fever, rheumatoid arthritis, rheumatic fever, osteoarthritis, decrease risk of MI, decrease risk of ischemic attack, maintain pregnancy

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4
Q

Salicylates SE

A

gastric upset, heartburn, anorexia, GI bleeding

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5
Q

Salicylates CI

A

NSAID allergy, bleeding disorder

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6
Q

Salicylates precautions

A

lactation, hypoprothrombinemia, decrease vitamin k, GI irritation

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7
Q

Salicylates Interactions

A

Anticoagulants, NSAIDs, antacids, carbonic anhydrase inhibitors

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8
Q

Nonsalicylates ex

A

acetaminophen

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9
Q

Nonsalicylates use

A

mild-mod pain, fever, manage pain with arthritic disorders

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10
Q

Nonsalicylates SE

A

urticaria, hemolytic anemia, pancytopenia, hypoglycemia, jaundice

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11
Q

Nonsalicylates CI

A

alcohol, salicylates, NSAIDs

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12
Q

Nonsalicylates precautions

A

Preg/lact, severe pain/fever

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13
Q

Nonsalicylates interactions

A

barbiturates, hydantoins, isoniazid, rifampin, loop diuretics

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14
Q

NSAIDs MOA

A

block COX-1 and COX-2

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15
Q

NSAIDs uses

A

pain with musculoskeletal disorders, mild-mod pain, dysmenorrhea, fever

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16
Q

NSAIDs SE

A

anorexia, dry mouth, constipation, abdominal pain, stomatitis, jaundice, anx/depres, sleepiness, insomnia, BP changes, urinary issues, blood component level issues, rashes, visual, disturbances (literally every side effect under the sun)

17
Q

NSAIDs CI

A

allergy to aspirin, preg/lact

18
Q

NSAIDs precautions

A

elderly, bleeding disorder, CV disease

19
Q

NSAIDs interactions

A

anticoagulants, lithium, cyclosporine, hydantoins, diuretics, antihypertensives, acetaminophen

20
Q

NSAIDs ex

A

-profen, -ac, indomethacin, meclofenamate, mefenamic, meloxicam, nabumetone, oxaprozin, piroxicam, tolmetin, celecoxib

21
Q

Antimigraines Ex

A

-triptan

22
Q

Antimigraines MOA

A

serotonin 5-HT receptor agonists

23
Q

Antimigraines SE

A

coronary artery vasospasm, arrhythmia, tachycardia, MI

24
Q

Antimigraines CI

A

Ischemic heart disease, hypertension, MAOI

25
Q

Antimigraines precautions

A

elderly, preg/lact

26
Q

Antimigraines interactions

A

cimetidine, contraceptives

27
Q

opioids ex

A

methadone, levorphanol, remifentanil, meperidine, hydromorphone, oxymorphone, oxycodone

28
Q

opioids MOA

A

interact with mu, delta, kappa receptors

29
Q

opioids uses

A

presurgery, relieve anxiety with certain conditions, severe pain, severe diarrhea, severe cough

30
Q

opioids SE

A

sedation, agitation/insomnia, depression in breathing, anorexia, changes in HR, urinary retention, rash

31
Q

opioids CI

A

acute bronchial asthma, emphysema, upper airway obstruction, head injury, convulsive disorders, severe hepatic/renal, ulcerative colitis

32
Q

opioids precautions

A

elderly, ppl who haven’t used before

33
Q

opioids interactions

A

alcohol, antihistamines, antidepressants, sedatives, phenothiazines, barbiturates

34
Q

opioid antagonists ex

A

naloxone, naltrexone

35
Q

`opioid antagonists use

A

opioid OD

36
Q

opioid antagonists SE

A

sweating, tachycardia, hypertension, tremors

37
Q

Local anesthesia ex

A

articaine, lidocaine, bupivacaine, chlorprocaine, mepivacaine, prilocaine, ropivacaine

38
Q

Pre-anesthetic types

A

opioid/antianxiety, cholinergic blocking (dry the upper respiratory tract), antiemetic

39
Q

General anesthesia ex

A

methohexital, midazolam, ketamine, fentanyl, droperidol