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HOSA Pharmacology simplified > Drugs that Affect the CNS > Flashcards

Drugs that Affect the CNS Flashcards

1
Q

CNS stimulants uses

A

ADHD, drug induced respiratory depression, post anesthesia respiratory depression, narcolepsy, obstructive sleep apnea, exogenous obesity

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2
Q

CNS stimulants SE

A

headache, dizzy, apprehension, disorientation, hyperactivity, cough, dyspnea, urinary retention, tachycardia, palpitations

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3
Q

CNS stimulants CI

A

ventilation disorders, cardiac problems, severe hypertension, hyperthyroidism

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4
Q

CNS stimulants precautions

A

respiratory illness, history of substance abuse, preg/lact

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5
Q

CNS stimulants interact

A

anesthetics, theophylline, contraceptives

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6
Q

CNS Stimulant types

A

amphetamines, analeptics, anorexiants

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7
Q

amphetamines ex

A

-amphetamine, -methylphenidate

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8
Q

analeptics ex

A

-modafinil, doxapram, caffeine

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9
Q

anorexiants ex

A

benzphetamine, diethylpropion, lorcaserin, phendimetrazine, phentermine

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10
Q

Cholinesterase inhibitors use

A

early and moderate stages of dementia associated with Alzheimer

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11
Q

cholinesterase inhibitors SE

A

anorexia, dizzy, headache

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12
Q

cholinesterase inhibitors CI

A

preg/lact

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13
Q

cholinesterase inhibitors precautions

A

bladder obstruction, seizure disorder, sick sinus syndrome, GI bleeding, asthma

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14
Q

cholinesterase inhibitors interact

A

anticholinergics, NSAIDs, theophylline, thiazide diuretics

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15
Q

cholinesterase inhibitors ex

A

donepezil, galantamine, rivastigmine, memantine

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16
Q

Benzodiazepines MOA

A

potentiate GABA

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17
Q

benzodiazepines uses

A

isolated episodes of intense anxiety, temporary use for those with severe functional impairment, preanesthetic sedation, muscle relaxation, convulsions, seizures, alcohol withdrawal

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18
Q

benzodiazepines SE

A

sedation, dizzy, headache, apathy, disorientation, anger, restlessness, constipation, dry mouth, visual disturbances

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19
Q

benzodiazepines CI

A

psychoses, acute narrow angle glaucoma, preg/lact

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20
Q

benzodiazepines precautions

A

elderly, debilitations

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21
Q

benzodiazepines interact

A

alcohol, analgesics, TCAs, antipsychotic, digoxin

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22
Q

benzodiazepines ex

A

-zepam, -zolam

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23
Q

nonbenzodiazepine antianxiety ex

A

buspirone, doxepin, hydroxyzine, meprobamate

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24
Q

benzodiazepine antidote

A

flumazenil

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25
Q

Barbiturates MOA

A

CNS depression

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26
Q

barbiturates uses

A

insomnia, convulsions, seizures, adjuncts to anesthesia

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27
Q

barbiturates SE

A

dizzy, drowsy, headache

28
Q

barbiturates CI

A

severe respiratory problems, comatose, history of drug/alcohol abuse, preg/lact

29
Q

barbiturates precautions

A

habitual alcohol use, mental health problems

30
Q

barbiturates interact

A

antidepressants, opioids, phenothiazines, cimetidine, alcohol

31
Q

barbiturates ex

A

pentobarbital, secobarbital

32
Q

nonbenzodiazepine sedatives ex

A

dexmedetomidine, eszopiclone, ramelteon, suvorexant, tasimelteon, zalepion, zolpidem

33
Q

SSRIs uses

A

depressive episodes, anxiety disorders, premenstrual dysphoric disorder, OCD, bulimia

34
Q

SSRIs SE

A

somnolence, dizzy, headache, insomnia, tremor, constipation, dry mouth, pharyngitis, runny nose, urinary retention

35
Q

SSRIs CI

A

preg/lact, cisapride, pimozide, carbamazepine

36
Q

SSRIs precautions

A

type 2 diabetes, cardiac disease, risk for suicide

37
Q

SSRIs interact

A

other antidepressants, cimetidine, NSAIDs, lithium

38
Q

SSRIs ex

A

fluoxetine, paroxetine, citalopram, escitalopram, sertraline, fluvoxamine, vortioxetine, vilazodone

39
Q

SNRIs uses

A

depressive episodes, depression accompanies by anxiety disorders, diabetic peripheral neuropathic pain, fibromyalgia, chronic muscle pain

40
Q

SNRIs SE

A

somnolence, headache, dizzy, blurred vision, photosensitivity, insomnia, nervousness, tremor, dry mouth, anorexia, constipation, bitter taste, tachycardia, palpitations, rash, flushing, sweating

41
Q

SNRIs CI

A

preg/lact, seizure, MI, cisapride, pimozide, carbamazepine

42
Q

SNRIs precautions

A

cardiac disease, hyperthyroid, suicide risk

43
Q

SNRIS interact

A

sedatives, warfarin, cimetidine, antihypertensives, MAOIs

44
Q

SNRIS ex

A

bupropion, desvenlafaxine, venlafaxine, duloxetine, levomilnacipran, nefazodone, trazodone

45
Q

TCAs ex

A

-iptyline, -ipramine, amozapine, doxepin

46
Q

TCAs MOA

A

inhibit serotonin or NE reuptake

47
Q

TCAs uses

A

depressive episodes, bipolar, OCD, chronic neuropathic pain, depression with anxiety, enuresis

48
Q

TCAs SE

A

sedation, dry mouth, visual disturbances, urinary retention, constipation, photosensitivity

49
Q

TCAs CI

A

recently took MAOIs, recent MI, children, preg/lact

50
Q

TCAs precautions

A

cardiac disease, hyperthyroid, seizure history, narrow angle glaucoma, increased intraocular pressure, urinary retention, suicide risk

51
Q

TCAs interactions

A

sedative, analgesics, cimetidine, MAOIs, adrenergics

52
Q

MAOIs ex

A

Takes Pride In Shanghai: Tranylcypromine, phenelzine, isocarboxazid, selegiline

53
Q

MAOIs uses

A

depressive episodes with therapy

54
Q

MAOIs SE

A

orthostatic hypotension, dizzy, headache, blurred vision, constipation, dry mouth, hypertensive crisis

55
Q

MAOIs CI

A

elderly, pheochromocytoma, liver/kidney disease, cerebrovascular disease, hypertension, headache history, CHF

56
Q

MAOIs precautions

A

seizure history, parkinsons symptoms, diabetes, hyperthyroid, suicide risk

57
Q

MAOIs interact

A

sedatives, analgesics, thiazide diuretics, meperidine, adrenergics, antitussives

58
Q

Lithium use

A

mood stabilizer for bipolar

59
Q

antipsychotics MOA

A

act on dopamine receptors

60
Q

antipsychotics uses

A

acute and chronic psychoses, bipolar, agitation, schizophrenia

61
Q

antipsychotics SE

A

sedation, headache, hypotension, dry mouth, nasal congestion, urticaria, photosensitivity, agitation, confusion, weight gain, high cholesterol

62
Q

antipsychotics CI

A

comatose, severe depression, bone marrow depression, bood dyscrasias, parkinsons, liver impairment, coronary artery disease, severe hypertension or hypotension

63
Q

antipsychotics precautions

A

respiratory disorder, glaucoma, prostatic hypertrophy, epilepsy, decreased renal function, peptic ulcer

64
Q

antipsychotics interact

A

anticholinergics, immunologics, alcohol

65
Q

antipsychotics 1st gen ex

A

chlorpromazine, fluphenazine, haloperidol, loxapine, perphenazine, pimozide, prochlorperazine, perphenazine, thioridazine, thiothixene, trifluoperazine

66
Q

antipsychotics atypical ex

A

aripiprazole, asenapine, ziprasidone, bexpiprazole, carlprazine, clozapine, iloperidone, lurasidone, olanzapine, paliperidone, quetiapine, risperidone

HOSA Pharmacology simplified (6 decks)

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