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HOSA Pharmacology simplified > Drugs that Affect the CNS > Flashcards

Drugs that Affect the CNS Flashcards

1
Q

CNS stimulants uses

A

ADHD, drug induced respiratory depression, post anesthesia respiratory depression, narcolepsy, obstructive sleep apnea, exogenous obesity

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2
Q

CNS stimulants SE

A

headache, dizzy, apprehension, disorientation, hyperactivity, cough, dyspnea, urinary retention, tachycardia, palpitations

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3
Q

CNS stimulants CI

A

ventilation disorders, cardiac problems, severe hypertension, hyperthyroidism

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4
Q

CNS stimulants precautions

A

respiratory illness, history of substance abuse, preg/lact

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5
Q

CNS stimulants interact

A

anesthetics, theophylline, contraceptives

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6
Q

CNS Stimulant types

A

amphetamines, analeptics, anorexiants

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7
Q

amphetamines ex

A

-amphetamine, -methylphenidate

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8
Q

analeptics ex

A

-modafinil, doxapram, caffeine

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9
Q

anorexiants ex

A

benzphetamine, diethylpropion, lorcaserin, phendimetrazine, phentermine

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10
Q

Cholinesterase inhibitors use

A

early and moderate stages of dementia associated with Alzheimer

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11
Q

cholinesterase inhibitors SE

A

anorexia, dizzy, headache

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12
Q

cholinesterase inhibitors CI

A

preg/lact

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13
Q

cholinesterase inhibitors precautions

A

bladder obstruction, seizure disorder, sick sinus syndrome, GI bleeding, asthma

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14
Q

cholinesterase inhibitors interact

A

anticholinergics, NSAIDs, theophylline, thiazide diuretics

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15
Q

cholinesterase inhibitors ex

A

donepezil, galantamine, rivastigmine, memantine

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16
Q

Benzodiazepines MOA

A

potentiate GABA

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17
Q

benzodiazepines uses

A

isolated episodes of intense anxiety, temporary use for those with severe functional impairment, preanesthetic sedation, muscle relaxation, convulsions, seizures, alcohol withdrawal

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18
Q

benzodiazepines SE

A

sedation, dizzy, headache, apathy, disorientation, anger, restlessness, constipation, dry mouth, visual disturbances

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19
Q

benzodiazepines CI

A

psychoses, acute narrow angle glaucoma, preg/lact

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20
Q

benzodiazepines precautions

A

elderly, debilitations

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21
Q

benzodiazepines interact

A

alcohol, analgesics, TCAs, antipsychotic, digoxin

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22
Q

benzodiazepines ex

A

-zepam, -zolam

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23
Q

nonbenzodiazepine antianxiety ex

A

buspirone, doxepin, hydroxyzine, meprobamate

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24
Q

benzodiazepine antidote

A

flumazenil

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25
Barbiturates MOA
CNS depression
26
barbiturates uses
insomnia, convulsions, seizures, adjuncts to anesthesia
27
barbiturates SE
dizzy, drowsy, headache
28
barbiturates CI
severe respiratory problems, comatose, history of drug/alcohol abuse, preg/lact
29
barbiturates precautions
habitual alcohol use, mental health problems
30
barbiturates interact
antidepressants, opioids, phenothiazines, cimetidine, alcohol
31
barbiturates ex
pentobarbital, secobarbital
32
nonbenzodiazepine sedatives ex
dexmedetomidine, eszopiclone, ramelteon, suvorexant, tasimelteon, zalepion, zolpidem
33
SSRIs uses
depressive episodes, anxiety disorders, premenstrual dysphoric disorder, OCD, bulimia
34
SSRIs SE
somnolence, dizzy, headache, insomnia, tremor, constipation, dry mouth, pharyngitis, runny nose, urinary retention
35
SSRIs CI
preg/lact, cisapride, pimozide, carbamazepine
36
SSRIs precautions
type 2 diabetes, cardiac disease, risk for suicide
37
SSRIs interact
other antidepressants, cimetidine, NSAIDs, lithium
38
SSRIs ex
fluoxetine, paroxetine, citalopram, escitalopram, sertraline, fluvoxamine, vortioxetine, vilazodone
39
SNRIs uses
depressive episodes, depression accompanies by anxiety disorders, diabetic peripheral neuropathic pain, fibromyalgia, chronic muscle pain
40
SNRIs SE
somnolence, headache, dizzy, blurred vision, photosensitivity, insomnia, nervousness, tremor, dry mouth, anorexia, constipation, bitter taste, tachycardia, palpitations, rash, flushing, sweating
41
SNRIs CI
preg/lact, seizure, MI, cisapride, pimozide, carbamazepine
42
SNRIs precautions
cardiac disease, hyperthyroid, suicide risk
43
SNRIS interact
sedatives, warfarin, cimetidine, antihypertensives, MAOIs
44
SNRIS ex
bupropion, desvenlafaxine, venlafaxine, duloxetine, levomilnacipran, nefazodone, trazodone
45
TCAs ex
-iptyline, -ipramine, amozapine, doxepin
46
TCAs MOA
inhibit serotonin or NE reuptake
47
TCAs uses
depressive episodes, bipolar, OCD, chronic neuropathic pain, depression with anxiety, enuresis
48
TCAs SE
sedation, dry mouth, visual disturbances, urinary retention, constipation, photosensitivity
49
TCAs CI
recently took MAOIs, recent MI, children, preg/lact
50
TCAs precautions
cardiac disease, hyperthyroid, seizure history, narrow angle glaucoma, increased intraocular pressure, urinary retention, suicide risk
51
TCAs interactions
sedative, analgesics, cimetidine, MAOIs, adrenergics
52
MAOIs ex
Takes Pride In Shanghai: Tranylcypromine, phenelzine, isocarboxazid, selegiline
53
MAOIs uses
depressive episodes with therapy
54
MAOIs SE
orthostatic hypotension, dizzy, headache, blurred vision, constipation, dry mouth, hypertensive crisis
55
MAOIs CI
elderly, pheochromocytoma, liver/kidney disease, cerebrovascular disease, hypertension, headache history, CHF
56
MAOIs precautions
seizure history, parkinsons symptoms, diabetes, hyperthyroid, suicide risk
57
MAOIs interact
sedatives, analgesics, thiazide diuretics, meperidine, adrenergics, antitussives
58
Lithium use
mood stabilizer for bipolar
59
antipsychotics MOA
act on dopamine receptors
60
antipsychotics uses
acute and chronic psychoses, bipolar, agitation, schizophrenia
61
antipsychotics SE
sedation, headache, hypotension, dry mouth, nasal congestion, urticaria, photosensitivity, agitation, confusion, weight gain, high cholesterol
62
antipsychotics CI
comatose, severe depression, bone marrow depression, bood dyscrasias, parkinsons, liver impairment, coronary artery disease, severe hypertension or hypotension
63
antipsychotics precautions
respiratory disorder, glaucoma, prostatic hypertrophy, epilepsy, decreased renal function, peptic ulcer
64
antipsychotics interact
anticholinergics, immunologics, alcohol
65
antipsychotics 1st gen ex
chlorpromazine, fluphenazine, haloperidol, loxapine, perphenazine, pimozide, prochlorperazine, perphenazine, thioridazine, thiothixene, trifluoperazine
66
antipsychotics atypical ex
aripiprazole, asenapine, ziprasidone, bexpiprazole, carlprazine, clozapine, iloperidone, lurasidone, olanzapine, paliperidone, quetiapine, risperidone

HOSA Pharmacology simplified (6 decks)

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