Antibiotics Flashcards

1
Q

Sulfonamides MOA

A

Bacteriostatic

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2
Q

Sulfonamides use

A

UTIs, acute otitis media, ulcerative colitis, burns (Mafenide and sulfadiazine)

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3
Q

Sulfonamides SE

A

anorexia, abdominal pain, stomatitis, chills, fever, crystalluria

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4
Q

Sulfonamides CI

A

Less than 2, pregnant/lactating

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5
Q

Sulfonamides precautions

A

Bronchial asthma

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6
Q

Sulfonamides interactions

A

anticoagulants, methotrexate, hydantoins

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7
Q

Penicillins MOA

A

Inhibit cell wall integrity

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8
Q

Penicillin types

A

Aminopenicillins, extended-spectrum, natural, penicillinase-resistant

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9
Q

Penicillins uses

A

UTIs, septicemia, meningitis, intra-abdominal infections, STIs, pneumonia

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10
Q

Penicillins SE

A

glossitis, stomatitis, dry mouth, gastritis

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11
Q

Penicillins precautions

A

asthma, bleeding disorders, GI disorders

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12
Q

Penicillins interactions

A

contraceptives, tetracycline, anticoagulants, beta-blockers

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13
Q

Cephalosporins MOA

A

target cell wall

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14
Q

Cephalosporins uses

A

respiratory infections, otitis media, bone/joint infections, interabdominal and genitourinary infections

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15
Q

cephalosporins SE

A

headache, dizziness, heartburn, fever, nephrotoxicity

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16
Q

Cephalosporins precautions

A

bleeding disorder

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17
Q

Cephalosporins interactions

A

aminoglycosides, anticoagulants, loop diuretics

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18
Q

Carbapenems ex

A

Meropenem, doripenem, televancin, oritavancin, vancomycin

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19
Q

Carbapenems MOA

A

inhibit cell wall activity

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20
Q

Carbapenems uses

A

intra-abdominal infections, meningitis, endocarditis, septicemia, UTIs, skin infections

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21
Q

Carbapenems SE

A

rash, chills, fever, nephrotoxicity, ototoxicity

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22
Q

Carbapenems CI

A

renal failure

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23
Q

Carbapenems Precautions

A

CNS disorder, seizures, hearing loss

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24
Q

Carbapenems interactions

A

probenecid

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25
Tetracyclines MOA
inhibit protein synthesis
26
Tetracyclines uses
rickettsial diseases, intestinal amebiasis, skin infections, chlamydia, helicobacter
27
Tetracyclines SE
Epigastric distress, stomatitis, sore throat, rash
28
Tetracyclines CI
pregnancy/lactation, less than 9
29
Tetracyclines interactions
Antacids, anticoagulants, contraceptives, digoxin
30
Aminoglycosides Ex
GNATS: Gentamycin, neomycin, amikacin, tobramycin, streptomycin
31
Aminoglycosides MOA
block protein synthesis
32
Aminoglycosides uses
gram neg, hepatic coma
33
Aminoglycosides SE
anorexia, rash/urticaria, nephro/oto/neurotoxicity
34
Aminoglycosides CI
hearing loss, myasthenia gravis, Parkinsons, pregnancy/lactation, long term use
35
Aminoglycosides precautions
elderly, neuromuscular disorders
36
Aminoglycosides interactions
cephalosporins, loop diuretics, general anesthetics
37
Macrolides Ex
ACE: azithromycin, clarithromycin, erythromycin
38
Macrolides MOA
change protein synthesis
39
Macrolides uses
acne/skin infections, upper respiratory infections
40
Macrolides SE
abdominal pain
41
Macrolides CI
liver disease
42
Macrolides precaution
myasthenia gravis, pregnant/lactating
43
Macrolides interactions
Antacids, digoxin, anticoagulants, clindamycin, lincomycin, chloramphenicol, theophylline
44
Lincosamides ex
Lincomycin, clindamycin, pirlimycin
45
Lincosamides use
serious infections where penicillin and erythromycin don't work
46
Lincosamides MOA
inhibit protein synthesis
47
Lincosamides SE
Abdominal pain, esophagitis, rash, blood dyscrasias
48
Lincosamides CI
cisapride, pimozide, minor infections
49
Lincosamides precautions
GI disorder, myasthenia gravis
50
Lincosamides interactions
antacids, neuromuscular blocking disorders
51
Daptomycin/Linezolid/Quinupristin/Dalfopristin use
skin infections, VREF
52
Daptomycin/Linezolid/Quinupristin/Dalfopristin SE
headache/dizziness, insomnia, rash, chills, fatigue, depression, nervousness
53
Daptomycin/Linezolid/Quinupristin/Dalfopristin CI
pregnant/lactating, PKU
54
Daptomycin/Linezolid/Quinupristin/Dalfopristin precautions
bone marrow depression, hypertension, hyperthyroidism
55
Daptomycin/Linezolid/Quinupristin/Dalfopristin interactions
NSAIDs, MAOIs, tyramine foods
56
Fluoroquinolones ex
-floxacin
57
Fluoroquinolones MOA
interfere with DNA/RNA synthesis
58
Fluoroquinolones use
lower respiratory infections, bone/joint, urinary tract, and skin infections, STIs
59
Fluoroquinolones SE
abdominal pain, dizziness, superinfections
60
Fluoroquinolones CI
less than 18, pregnancy
61
Fluoroquinolones precautions
diabetes, seizures, elderly, dialysis
62
Fluoroquinolones interactions
theophylline, cimetidine, anticoagulants, antacids, NSAIDs