Drugs that act on the kidney Flashcards
Examples of Loop Diuretics
Furosemide
Bumetanide
What do Loop Diuretics do?
They block, sodium potassium and chloride pump
Excretion
Example of Potassium paring Diuretics
Spironolactone
Amilorid
Potassium Sparing diuretics act at?
Distal tubule and collecting duct
Loop diuretics act at?
Ascending Loop of Henle
Loop diuretics are
Very powerful
Act within 1 hour
Thiazide diuretic drugs
Bendroflumethazide
Thiazide diuretics act in the?
Distal tubule
What do thiazide diuretics do?
Stops reabsorption
Blocks Cl pump
Increases Na+ and Cl excretion
Dosage must be balanced to allow urine production to prevent water intoxication
Antidiuretics
Vasopressin
Antidiuretics
Injection/infusion only
Short duration
Increases BP
Desmopressin
Antidiuretic
Nasal Spray and Tablet
Long duration
Antidiuretic drugs
Vasopressin
Desmopressin
Which diuretic is used for central diabetes insipidus
Antidiuretics
Antidiuretics act in
Collecting tubule