Antihypertensive Drugs Flashcards
ACE Inhibitors block your body from producing..
Angiotensin 2
What determines Cardiac Output?
Venous Tone
Heart Rate
Blood Volume
Vol of blood pumped out
When angiotensin 2 enters your blood stream your blood vessels
Vasoconstriction causing high BP
ACE Inhibitors side effects..
Dry Cough
Rash
Renal Problems
Hypotension
Example of ACE inhibitors..
Captopril
Trandolapril
Ramipril
Lisionpril
A-Blockers
Block the action of NAdr and adrenaline on blood vessels > Vasodilation
Examples of A-blockers
Prazosin
Doxazosin
Terazosin
B-blockers act on the
sympathetic nervous system
Reduce HR?
Increases blood flow to the kidneys?
Decreases Renin secretion?
Blocks Vasoconstriction
B-blockers
Examples of B-blockers
Atenolol Metoprolol Bisoprolol Propranolol Sotalol
B-blockers side effects
Lethargy Achy limbs Erectile dysfunction Raynaud's disease Asthma
???? can dilate arteries, reduce heart contraction and reduce HR
Calcium Channel Blockers
Examples of Calcium Channel Blockers
more potent on blood vessels than heart
Nofedipine
Amlodipine
Nicardipine
Examples of Calcium Channel Blockers
more potent on heart than blood vessels
Verapamil
Diltiazem
Increase AV Node conduction
Increase arterial tone
Increase myocardial contractility
Increase HR
Calcium Channel Blockers
Increase urine output
Decrease blood volume
Diuretics
Examples of thiazide-like diuretics
Indapmide
Chloralidone
Bendroflumethiazide
Side effects of thiazide-like and diuretics
Reduced potassium
Reduced Insulin
Increase plasma lipids and urate > gout
Erectile dysfunction
Examples of Potassium Sparing diuretics
Amilorid
Spironolactone
Useful for treating severe hypertension
May cause gout - hypokalaemia
Loop diuretics
