Drugs Test 3 Flashcards
ACE inhibitors
Captopril (Capoten)
Enalapril (Vasotec)
Lisinopril (Prinivil)
Ace inhibitors KeyPoint
Ace inhibitors prevent the conversion of angiotensin, one to angiotensin two leading to a fall in blood pressure
Adverse effects associated with ace, inhibitors are related to the effects of vasodilation and alterations in blood flow
CNS affects: Syncope, dizziness, headache
Dermatological reactions, alopecia rash
Cough
cardiovascular effects, tachycardia, heart failure, arrhythmias, hypotension
Liver damage, renal damage, G.I. effects
Angiotensin II receptor blockers
Losartan (Cozar)
Angiotensin two receptor blocker’s key points
Prevent the body from responding to angiotensin two, causing a loss of effectiveness of the renin angiotensin system by blocking the angiotension, receptor and blood vessels
Calcium channel blockers
Diltiazem (Cardizem)
Amlodipine ( Nirvasc)
Verapamil (Calan)
Calcium channel blockers, key points
Main use of calcium channel blockers is for the treatment of angina
Calcium channel blockers interfere with the influx of calcium, decreasing the ability of muscles to contract, which leads to vasodilation, which in turn reduces blood pressure 
Vasodilators
Nitroprusside (Nitropress)
Sympathetic, nervous system blockers
Beta blockers
Metoprolol
Atenolol
Beta blocker KeyPoint
Block, vasoconstriction, decreased heart rate, decreased cardiac muscle contractions, and tend to increase blood flow to the kidneys, leading to a decrease in the release of renin
Antianginal agent
Nitroglycerin (Nitro-Stat)
Nitrate key points
Nitrates cause blood vessels to relax and dilate. This results in a drop and peripheral resistance and blood pressure and a decrease in Venus return to the heart. These actions will decrease myocardial workload, and can restore the appropriate balance in the supply and demand ratio in the heart.
No trades are available in many forms at Barry, and time of onset and duration of action. Fast acting nitrate are used to treat a cute anginal attacks. Slower acting nitrates are used to prevent anginal attack from occurring. 
Cardiac glycosides
Digoxin (Lanoxin)
Digoxin KeyPoint
The cardiac glycoside digoxin increases the movement of calcium into the heart muscle. This results in increased force of contraction, which increases blood flow to the kidneys, causing a diuretic effect, slows the heart rate, and slows conduction through the AV node. All of these affects, decrease the hearts Workload
Bile acid sequestrants
Cholestyramine (Questran)
Bile acids sequestrants key points
Prevent the reabsorption of bile salts, with your high in cholesterol. Consequently, the Liverpool cholesterol from the blood to make a nubile acid, lowering the serum cholesterol level.
Patients need to learn how to mix powders are, if taking the tablet form, the importance of swallowing the tablet hall, and not cutting, crushing, or chewing it. Dosage should not be taken with other drugs to avoid problems with absorption.
G.I. problems are often reported when using bile acids sequestrants, including nausea, bloating, and constipation 
HMG CoA reductase inhibitor
Atrovastatin (Lipitor)
Simvastatain (Zocor)