DRUGS: Nitroglycerin (Nitrostat, Nitro-Bid, Tridil)

Question 1

Nitroglycerin (Nitrostat, Nitro-Bid, Tridil): Class

Answer 1

vasodilator

Question 2

Nitroglycerin (Nitrostat, Nitro-Bid, Tridil): Mechanism of Action

Answer 2

relaxes smooth muscle, reduces preload and afterload which decreases work of the heart therefor 02 demand decreases

Question 3

Nitroglycerin (Nitrostat, Nitro-Bid, Tridil): Indications

Answer 3

angina pectoris(acute),
hypertension

Question 4

Nitroglycerin (Nitrostat, Nitro-Bid, Tridil): Contraindications

Answer 4

hypotension, ICB, ED meds within 48hrs, administration within 24 hrs

Question 5

Nitroglycerin (Nitrostat, Nitro-Bid, Tridil): Adverse Reactions

Answer 5

headache,
dizziness,
tachycardia,
muscle twitching,
vomiting

Question 6

Nitroglycerin (Nitrostat, Nitro-Bid, Tridil): Drug Interactions

Answer 6

not compatible with IV drugs, effects with other vasodilators

Question 7

Nitroglycerin (Nitrostat, Nitro-Bid, Tridil): Route

Answer 7

SL

Question 8

Nitroglycerin (Nitrostat, Nitro-Bid, Tridil): Dosage & Administration ADULTS

Answer 8

Adults
0.4 mg SL repeated 3-5m until max 3 doses. SL spray 0.4 mg 1-2 sprays. Iv 10-20mcg/min increasing 5-10 mcg/min every 5min until desired effect.

Question 9

Nitroglycerin (Nitrostat, Nitro-Bid, Tridil): Dosage and Administration PEDIATRICS

Answer 9

Pediatrics
not recommended for children

Question 10

Nitroglycerin (Nitrostat, Nitro-Bid, Tridil): Duration of Action

Answer 10

Onset: 1-3 Minutes
Peak 5-10 Minutes
Duration: SL 20-30 minutes
Duration: IV 1-10 minutes after discontinuation of infusion

Question 11

Nitroglycerin (Nitrostat, Nitro-Bid, Tridil): Special Considerations

Answer 11

Pregnancy Safety: Has been used safely during pregnancy.
Category C, caution when breastfeeding and monitor infants. Keep airtight due to decomp from light and heat. May sting. HypoT mostly in older people.