DRUGS: Aspirin (Acetylsalicylic Acid)

Question 1

Aspirin: Class

Answer 1

Platelet inhibitor, anti-inflammatory agent

Question 2

Aspirin: Mechanism of Action

Answer 2

Prevents the formation of thromboxane A2, which causes platelets to clump together (aggregate) and form plugs that cause obstruction or constriction; has antipyretic and analgesic properties

Question 3

Aspirin: Indications

Answer 3

New-onset chest discomfort that suggests ACS.

Question 4

Aspirin: Contraindications

Answer 4

Hypersensitivity. Relatively contraindicated in patients with active ulcers disease or asthma.

Question 5

Aspirin: Adverse Reactions & Side Effects

Answer 5

Bronchospasm
Anaphylaxis
Wheezing in Allergic Patients
Prolonged Bleeding
GI Bleeding
Epigastric distress
Nausea / Vomiting
Heartburn
Reye Syndrome

Question 6

Aspirin: Drug Interactions

Answer 6

Use with caution in patients allergic to NSAIDs

Question 7

Aspirin: Route

Answer 7

Oral (Chewable tablet(s) )

Question 8

Aspirin: Dosage and Administration - ADULT

Answer 8

Adult: 160 to 325 mg PO Chewing is preferred to swallowing

Question 9

Aspirin: Dosage and Administration - PEDIATRIC

Answer 9

Pediatric: Not Recommended

Question 10

Aspirin: Duration of Action

Answer 10

Onset: 5-30 Minutes
Peak: 1-3 Hours
Duration: 3-6 Hours s