Drugs Mentioned in Lecture (aka Misc) Flashcards

1
Q

Cyclophosphamide

A

Immunosuppressant

Therapeutic Uses:

•nephrotic syndrome

-2nd line to steroids

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2
Q

Cyclosporine

A

Immunosuppressant

Therapeutic Uses:

  • transplant
  • nephrotic syndrome

-2nd line to steroids

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3
Q

Trimethoprim/Sulfamethoxazole (Bactrim)

A
  • binds to luminal Na+ channel in prinicipal cell
  • causes hyperkalemia
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4
Q

Phenoxybenzamine

A

Alpha Antagonist

Therapeutic Uses:

  • pheochromocytoma
  • bladder obstruction
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5
Q

Lithium

A
  • causes kidney damage
  • induces nephrogenic diabetes insipidus
  • can lead to microcysts in the kidney
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6
Q

Corticosteroids

A

Immunosuppressant

Anti-Inflammatory

Therapeutic Uses:

  • MPGN
  • RPGN
  • IgA if proteinuira present
  • lupus nephritis
  • systemic vasculitis
  • nephrotic syndromes
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7
Q

Radiocontrast Media

A
  • damages kidney
  • ATN within 72 hours

(choesterol emboli takes 2-8 weeks)

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8
Q

Calcium Chloride

A
  • Antagonizing membrane effects of K+
  • hyperkalemia
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9
Q

Kayexalate

A
  • Cation Exchange Resin
  • takes up K+ in gut, releases Na+
  • Side Effect: intestinal necrosis due to sorbitol preparation used to deliver
  • not for patients who have had recent surgery
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10
Q

Conivaptan

A
  • V2 Receptor Antagonist
  • SIADH
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11
Q

Tolvaptan

A
  • V2 Receptor Antagonist
  • SIADH
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12
Q

Canagliflozin

A

SGLT2 Inhibitor

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13
Q

Dapagliflozin

A

SGLT2 Inhibitor

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14
Q

Empagliflozin

A

SGLT2 Inhibitor

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