Drugs Mentioned in Lecture (aka Misc) Flashcards
1
Q
Cyclophosphamide
A
Immunosuppressant
Therapeutic Uses:
•nephrotic syndrome
-2nd line to steroids
2
Q
Cyclosporine
A
Immunosuppressant
Therapeutic Uses:
- transplant
- nephrotic syndrome
-2nd line to steroids
3
Q
Trimethoprim/Sulfamethoxazole (Bactrim)
A
- binds to luminal Na+ channel in prinicipal cell
- causes hyperkalemia
4
Q
Phenoxybenzamine
A
Alpha Antagonist
Therapeutic Uses:
- pheochromocytoma
- bladder obstruction
5
Q
Lithium
A
- causes kidney damage
- induces nephrogenic diabetes insipidus
- can lead to microcysts in the kidney
6
Q
Corticosteroids
A
Immunosuppressant
Anti-Inflammatory
Therapeutic Uses:
- MPGN
- RPGN
- IgA if proteinuira present
- lupus nephritis
- systemic vasculitis
- nephrotic syndromes
7
Q
Radiocontrast Media
A
- damages kidney
- ATN within 72 hours
(choesterol emboli takes 2-8 weeks)
8
Q
Calcium Chloride
A
- Antagonizing membrane effects of K+
- hyperkalemia
9
Q
Kayexalate
A
- Cation Exchange Resin
- takes up K+ in gut, releases Na+
- Side Effect: intestinal necrosis due to sorbitol preparation used to deliver
- not for patients who have had recent surgery
10
Q
Conivaptan
A
- V2 Receptor Antagonist
- SIADH
11
Q
Tolvaptan
A
- V2 Receptor Antagonist
- SIADH
12
Q
Canagliflozin
A
SGLT2 Inhibitor
13
Q
Dapagliflozin
A
SGLT2 Inhibitor
14
Q
Empagliflozin
A
SGLT2 Inhibitor