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Renal > Drugs Acting on the Angiotensin System > Flashcards

Drugs Acting on the Angiotensin System Flashcards

1
Q

Catopril

A

ACE inhibitor

MOA:

•inhibits angiotensin converting enzyme and formation of angiotensin II –> decreases aldosterone secretion

Therapeutic Uses:

  • hypertension
  • heart failure
  • diabetic neuropathy

Side Effects:

  • angiotedema
  • cough (bradykinin)
  • teratogenicity
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2
Q

Lisinopril

A

ACE inhibitor

MOA:

•inhibits angiotensin converting enzyme and formation of angiotensin II –> decreases aldosterone secretion

Therapeutic Uses:

  • hypertension
  • heart failure
  • diabetic neuropathy

Side Effects:

  • angiotedema
  • cough (bradykinin)
  • teratogenicity
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3
Q

Enalapril

A

ACE inhibitor

MOA:

•inhibits angiotensin converting enzyme and formation of angiotensin II –> decreases aldosterone secretion

Therapeutic Uses:

  • hypertension
  • heart failure
  • diabetic neuropathy

Side Effects:

  • angiotedema
  • cough (bradykinin)
  • teratogenicity
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4
Q

Benazepril

A

ACE inhibitor

MOA:

•inhibits angiotensin converting enzyme and formation of angiotensin II –> decreases aldosterone secretion

Therapeutic Uses:

  • hypertension
  • heart failure
  • diabetic neuropathy

Side Effects:

  • angiotedema
  • cough (bradykinin)
  • teratogenicity
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5
Q

Ramipril

A

ACE inhibitor

MOA:

•inhibits angiotensin converting enzyme and formation of angiotensin II –> decreases aldosterone secretion

Therapeutic Uses:

  • hypertension
  • heart failure
  • diabetic neuropathy

Side Effects:

  • angiotedema
  • cough (bradykinin)
  • teratogenicity
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6
Q

Losartan

A

Angiotensin Receptor Blockers (ARBs)

MOA:

•blocks angiotensin II receptors

Therapeutic Uses:

  • hypertension
  • heart failure
  • diabetic neuropathy

Side Effects:

  • teratogenicity
  • hyperkalemia
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7
Q

Valsartan

A

Angiotensin Receptor Blockers (ARBs)

MOA:

•blocks angiotensin II receptors

Therapeutic Uses:

  • hypertension
  • heart failure
  • diabetic neuropathy

Side Effects:

  • teratogenicity
  • hyperkalemia
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8
Q

Candesartan

A

Angiotensin Receptor Blockers (ARBs)

MOA:

•blocks angiotensin II receptors

Therapeutic Uses:

  • hypertension
  • heart failure
  • diabetic neuropathy

Side Effects:

  • teratogenicity
  • hyperkalemia
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9
Q

Aliskiren

A

Direct Renin Antagonist

MOA:

•direct renin antagonist

Therapeutic Uses:

  • hypertension
  • heart failure

Side Effects:

  • angioedema
  • diarrhea
  • hyperkalemia
  • teratogenicity
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Renal (26 decks)

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