Drugs in pathology Flashcards

1
Q

clofibrate

A

Cholesterol stone

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2
Q

aminoglycosides
lead
dye

A

Acute tubular necrosis

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3
Q

NSAIDS,penicillin,diuretics

A

Acute interstitial nephritis

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4
Q

Chronic use of Analgesic-Aspirin

A

Renal papillary necrosis

other
DM
Sickle cell disease
Severe acute pyelonephritis

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5
Q

NSAIDS,Penicilliamine

A

Membranous nephropathy

other
hepatitis B or C
Solid tumors,SLE

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6
Q

Tamoxifen

A

Endometrial polyps

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7
Q

OC pills

A

Hepatic Adenoma

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8
Q

Lithium,Demeclocyclin

A

Nephrogenic Diabetes insipidus

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9
Q

Cyclophophamide

A

SIADH

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10
Q

Steroids long term

A

Cushings syndrome

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11
Q

Adverse drug reaction

A

Stevens johnson syndrome

Toxic epidermal necrolysis

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12
Q

alkylating agents -chemotherapy

A

Leukemia/Lymphoma

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13
Q

Aspirin

A

irreversible inhibits cyclooxygenase in platelets

lacks TXA2

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14
Q

Methotrexate

A

Folate antagonist

Folate defn

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15
Q

primaquine,sulpha drugs

fave beans

A

G6PD defn

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16
Q

procainamide,Hydralazine,isoniazid

A

Drug induced Lupus

Anti histone antibody

17
Q

penicillin

cephalosporins

A
IgG mediated immune hemolytic anemia
warm agglutinins
other
SLE
CLL