DRUGS FOR SEIZURE

Question 1

DOC for primary generalized epilepsy

Answer 1

Valproic Acid

Question 2

It Increase GABA and blocks T-type Calcium channel
in the brain

Answer 2

Valproic Acid

Question 3

It is important in absence seizure

Answer 3

T-type

Question 4

Secondary options for epilepsy

Answer 4

Phenytoin, Carbamazepine

Question 5

Drug for Tonic- clonic Seizure

Answer 5

Phenytoin

Question 6

It Increases risk for Stevens-Johnson syndrome (SJS)

Answer 6

Phenytoin

Question 7

A carbonic anhydrase inhibitor
Blocks T-type Calcium channel
Prolongs sodium channel inactivation

Answer 7

Zonisamide

Question 8

For tonic- clonic seizure
Inhibits Sodium channel and potentiates the inhibitory activity of GABA
May block glutamate
ADR: Teratogenic

Answer 8

Topiramate

Question 9

For Primary GTCS in adults and children <6 years old
For juvenile myoclonic and partial seizure

Answer 9

Levetiracetam

Question 10

Decreases the neuronal activity and increases the seizure threshold

Answer 10

Primidone

Question 11

1,5 benzodiazepine, enhances inhibitory effect of GABA by increasing permeability of chloride ions

Answer 11

Clobazam