Dementia part 2 Flashcards
a large protein leftover fragment which
disrupts the cell to cell communications.
Beta amyloid
initiates the neuron’s transport
system of nutrients and essential materials are being
deformed and cause “Neurofibrillary tangles” that
disrupts the transport system.
Tau proteins
Stage:
MMSE score: 26- 21
Memory loss
Confusion about the location of a familiar place
Takes long time to accomplish daily/ normal task
MILD ALZHEIMER’S DISEASE
Stage:
Mini Mental State Examination score: 20-10
Increased memory loss and confusion
Shorten attention span
Problem recognizing friends
MODERATE ALZHEIMER’S DISEASE
Stage:
MMSE score: 9-0
Complete dependence to others
All sense of self seem to vanish
SEVERE ALZHEIMER’S DISEASE
Maintain cognitive functioning and activities of daily
living as long as possible, with a secondary goal to treat
the psychiatric and behavioral symptoms. is the ______
THERAPEUTIC GOAL
LABORATORY AND IMAGING TEST for alzheimer’s
MRI
CT
Thyroid hormone levels
Drug For moderate to severe dementia
Usually, these are used in MONOTHERAPY or in
combination with CHOLINESTERASE
INHIBITORS
Memantine
Dementia combination therapy
Memantine + Donepezil