Drugs For CHD Flashcards
0
Q
What are the problems with nitrates?
A
Tolerance develops, short shelf life, many side effects
1
Q
What is the most commonly used nitrate?
A
GTN
2
Q
How do nitrovasodilators work?
A
Produce nitric oxide which increases cGMP in muscle class causing muscle to relax and vessel dilates.
3
Q
What do nitro vasodilators dilate?
A
Both arteries and veins
4
Q
What are the side effects of nitrates?
A
Throbbing headache, dizziness, lowered BP
5
Q
Which other drugs should you be careful with when taking nitrates?
A
BP lowering drugs
6
Q
What are lipoproteins?
A
Packages of proteins with lipids
7
Q
How do statism work?
A
Developed as HMG-CoA reductase inhibitors but may have other mechanisms
8
Q
What are the side effects of statins?
A
GI upsets, abnormal liver tests, muscle problems
