Drugs and the eye Flashcards

1
Q

What is Fluorescin Used for?

A
Intraocular Pressure
Detecting Epithelial defects
-Corneal abrasion
-corneal ulcer
-Keratitis
IV Angiography for retinal disorders
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2
Q

What are the indications for Topical Anesthetic?

A

Measuring IOP
Superficial Surgery
Eval of painful Eye

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3
Q

What are the Meds used for Topical anesthetic in the eye?

A

Proparacaine
Tetracaine
Lidocaine

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4
Q

What drugs are used for Pupillary Dilation?

A

Cholinergic Blockers-PNS-lytic

Adrenergic Stimulants-SNS

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5
Q

What are the Tx for Allergic Conjunctivitis?

A
Tear substitutes
Decongestants
Decongestants/Antihistamines
Mast Cell Stabilizers
NSAIDS,
Cortiosteroids
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6
Q

What is the Tx of Bacterial Conjunctivitis?

A

Aminoglycosides: Tobramycin
Erythromycin
Bacitracin
Fluoroquinolones

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7
Q

What is the Tx of Herpes Simplex Keratitis?

A
Trifluorothymidine
Gancyclovir
Acyclovir
Famcyclovir
Valacyclovir
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8
Q

Why should Topical Steroids be avoided?

A

Exacerbate Herpes Keratitis
Elevate IOP
Cause Cataracts

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9
Q

What are the Tx for Glaucoma?

A
Prostaglandin Analouges
B Adrenergic Antagonis 
Cholinergic Agents
Adrenergic Agonits
Carbonic Anhydrase Inh
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10
Q

What is the MOA of the Prostaglandin analogs used for Gaucoma? Side Effects?

A

Increases Uveoscleral outflow
Inc Iris Pigmentation
Darkens Periocular skin

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11
Q

What is the safest glaucoma med in pregnancy?

A

Adrenergic agonists

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12
Q

What is the MOA of the Beta Ad Blockers used for Gaucoma? Side Effects?

A

Dec Aqueous Production

Bradycardia
Red Card output

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13
Q

What is the MOA of the Cholinergic Agonists used for Gaucoma? Side Effects?

A
Inc Aqueous outflow through trabecular meshwork
SA: Dec Vision
Brow ache
Retinal Detch
Lacrimation, N/V/D
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14
Q

Whatof the Side Effects of Carbonic Anhydrase used for Gaucoma?

A

Electrolyte Imbalances
Renal Stones
Altered taste
Aplastic Anemia

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15
Q

What are the Irreversible SA of Alpha 1 blockers? Tamoxifen? Ethambutol?

A

Intraop floppy iris
High dose => cornea, retina
Optic Neuropathy

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16
Q

What are the Irreversible SA of Corticosteroids? Chloroquine? Topiramate?

A

Glaucoma
Maculopathy
Angle Closure Glaucoma

17
Q

What are the reversible SA of Anticholinergics?

A

Dec Near Vision
Pupillary Dilation
Glaucoma

18
Q

What are the reversible SA of Isotretinoin?

A

DTS, Conjunctivitis, Cataracts

19
Q

What are the reversible SA of Amiodarone?

A

Corneal Changes

20
Q

What are the reversible SA of Chlorpromazine?

A

Corneal/lense opacity

21
Q

What are the reversible SA of Bisphosphonates?

A

Red eye, photophobia, deep pain

22
Q

What are the reversible SA of Alpha interferon?

A

Vascular Retinopathy

AION

23
Q

What are the reversible SA of Rifabutin?

A

Severe Uveitis

24
Q

What are the reversible SA of HMG-CoA reductase inhibitors (STATINS)?

A
Myopathy
Diplopia
Ptosis
Opthalmoplegia
Cataracts
25
What are the reversible SA of Sildenafil?
Blue Color Tinge, AION-like synd
26
What are the reversible SA of TNF inhibitors used with infliximab?
Sensory Neuropathy, Guillian Barre synd, CN palsy meningitis and MS like Synd
27
What are the SA of Digitalis at above Reccomended Doses?
Blurred vision, and chromatopsia
28
What are the SA of Dilantin at above Reccomended Doses?
Nystagmus
29
What are the SA of Thiordazine at above Reccomended Doses?
Pigmentary Retinopathy
30
Which Drugs should not be used to dilate the pupil?
Atropine or Scopolamine