Drugs and the eye Flashcards

1
Q

What is Fluorescin Used for?

A
Intraocular Pressure
Detecting Epithelial defects
-Corneal abrasion
-corneal ulcer
-Keratitis
IV Angiography for retinal disorders
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2
Q

What are the indications for Topical Anesthetic?

A

Measuring IOP
Superficial Surgery
Eval of painful Eye

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3
Q

What are the Meds used for Topical anesthetic in the eye?

A

Proparacaine
Tetracaine
Lidocaine

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4
Q

What drugs are used for Pupillary Dilation?

A

Cholinergic Blockers-PNS-lytic

Adrenergic Stimulants-SNS

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5
Q

What are the Tx for Allergic Conjunctivitis?

A
Tear substitutes
Decongestants
Decongestants/Antihistamines
Mast Cell Stabilizers
NSAIDS,
Cortiosteroids
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6
Q

What is the Tx of Bacterial Conjunctivitis?

A

Aminoglycosides: Tobramycin
Erythromycin
Bacitracin
Fluoroquinolones

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7
Q

What is the Tx of Herpes Simplex Keratitis?

A
Trifluorothymidine
Gancyclovir
Acyclovir
Famcyclovir
Valacyclovir
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8
Q

Why should Topical Steroids be avoided?

A

Exacerbate Herpes Keratitis
Elevate IOP
Cause Cataracts

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9
Q

What are the Tx for Glaucoma?

A
Prostaglandin Analouges
B Adrenergic Antagonis 
Cholinergic Agents
Adrenergic Agonits
Carbonic Anhydrase Inh
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10
Q

What is the MOA of the Prostaglandin analogs used for Gaucoma? Side Effects?

A

Increases Uveoscleral outflow
Inc Iris Pigmentation
Darkens Periocular skin

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11
Q

What is the safest glaucoma med in pregnancy?

A

Adrenergic agonists

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12
Q

What is the MOA of the Beta Ad Blockers used for Gaucoma? Side Effects?

A

Dec Aqueous Production

Bradycardia
Red Card output

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13
Q

What is the MOA of the Cholinergic Agonists used for Gaucoma? Side Effects?

A
Inc Aqueous outflow through trabecular meshwork
SA: Dec Vision
Brow ache
Retinal Detch
Lacrimation, N/V/D
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14
Q

Whatof the Side Effects of Carbonic Anhydrase used for Gaucoma?

A

Electrolyte Imbalances
Renal Stones
Altered taste
Aplastic Anemia

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15
Q

What are the Irreversible SA of Alpha 1 blockers? Tamoxifen? Ethambutol?

A

Intraop floppy iris
High dose => cornea, retina
Optic Neuropathy

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16
Q

What are the Irreversible SA of Corticosteroids? Chloroquine? Topiramate?

A

Glaucoma
Maculopathy
Angle Closure Glaucoma

17
Q

What are the reversible SA of Anticholinergics?

A

Dec Near Vision
Pupillary Dilation
Glaucoma

18
Q

What are the reversible SA of Isotretinoin?

A

DTS, Conjunctivitis, Cataracts

19
Q

What are the reversible SA of Amiodarone?

A

Corneal Changes

20
Q

What are the reversible SA of Chlorpromazine?

A

Corneal/lense opacity

21
Q

What are the reversible SA of Bisphosphonates?

A

Red eye, photophobia, deep pain

22
Q

What are the reversible SA of Alpha interferon?

A

Vascular Retinopathy

AION

23
Q

What are the reversible SA of Rifabutin?

A

Severe Uveitis

24
Q

What are the reversible SA of HMG-CoA reductase inhibitors (STATINS)?

A
Myopathy
Diplopia
Ptosis
Opthalmoplegia
Cataracts
25
Q

What are the reversible SA of Sildenafil?

A

Blue Color Tinge, AION-like synd

26
Q

What are the reversible SA of TNF inhibitors used with infliximab?

A

Sensory Neuropathy, Guillian Barre synd, CN palsy meningitis and MS like Synd

27
Q

What are the SA of Digitalis at above Reccomended Doses?

A

Blurred vision, and chromatopsia

28
Q

What are the SA of Dilantin at above Reccomended Doses?

A

Nystagmus

29
Q

What are the SA of Thiordazine at above Reccomended Doses?

A

Pigmentary Retinopathy

30
Q

Which Drugs should not be used to dilate the pupil?

A

Atropine or Scopolamine