Drugs and the eye Flashcards
What is Fluorescin Used for?
Intraocular Pressure Detecting Epithelial defects -Corneal abrasion -corneal ulcer -Keratitis IV Angiography for retinal disorders
What are the indications for Topical Anesthetic?
Measuring IOP
Superficial Surgery
Eval of painful Eye
What are the Meds used for Topical anesthetic in the eye?
Proparacaine
Tetracaine
Lidocaine
What drugs are used for Pupillary Dilation?
Cholinergic Blockers-PNS-lytic
Adrenergic Stimulants-SNS
What are the Tx for Allergic Conjunctivitis?
Tear substitutes Decongestants Decongestants/Antihistamines Mast Cell Stabilizers NSAIDS, Cortiosteroids
What is the Tx of Bacterial Conjunctivitis?
Aminoglycosides: Tobramycin
Erythromycin
Bacitracin
Fluoroquinolones
What is the Tx of Herpes Simplex Keratitis?
Trifluorothymidine Gancyclovir Acyclovir Famcyclovir Valacyclovir
Why should Topical Steroids be avoided?
Exacerbate Herpes Keratitis
Elevate IOP
Cause Cataracts
What are the Tx for Glaucoma?
Prostaglandin Analouges B Adrenergic Antagonis Cholinergic Agents Adrenergic Agonits Carbonic Anhydrase Inh
What is the MOA of the Prostaglandin analogs used for Gaucoma? Side Effects?
Increases Uveoscleral outflow
Inc Iris Pigmentation
Darkens Periocular skin
What is the safest glaucoma med in pregnancy?
Adrenergic agonists
What is the MOA of the Beta Ad Blockers used for Gaucoma? Side Effects?
Dec Aqueous Production
Bradycardia
Red Card output
What is the MOA of the Cholinergic Agonists used for Gaucoma? Side Effects?
Inc Aqueous outflow through trabecular meshwork SA: Dec Vision Brow ache Retinal Detch Lacrimation, N/V/D
Whatof the Side Effects of Carbonic Anhydrase used for Gaucoma?
Electrolyte Imbalances
Renal Stones
Altered taste
Aplastic Anemia
What are the Irreversible SA of Alpha 1 blockers? Tamoxifen? Ethambutol?
Intraop floppy iris
High dose => cornea, retina
Optic Neuropathy
What are the Irreversible SA of Corticosteroids? Chloroquine? Topiramate?
Glaucoma
Maculopathy
Angle Closure Glaucoma
What are the reversible SA of Anticholinergics?
Dec Near Vision
Pupillary Dilation
Glaucoma
What are the reversible SA of Isotretinoin?
DTS, Conjunctivitis, Cataracts
What are the reversible SA of Amiodarone?
Corneal Changes
What are the reversible SA of Chlorpromazine?
Corneal/lense opacity
What are the reversible SA of Bisphosphonates?
Red eye, photophobia, deep pain
What are the reversible SA of Alpha interferon?
Vascular Retinopathy
AION
What are the reversible SA of Rifabutin?
Severe Uveitis
What are the reversible SA of HMG-CoA reductase inhibitors (STATINS)?
Myopathy Diplopia Ptosis Opthalmoplegia Cataracts
What are the reversible SA of Sildenafil?
Blue Color Tinge, AION-like synd
What are the reversible SA of TNF inhibitors used with infliximab?
Sensory Neuropathy, Guillian Barre synd, CN palsy meningitis and MS like Synd
What are the SA of Digitalis at above Reccomended Doses?
Blurred vision, and chromatopsia
What are the SA of Dilantin at above Reccomended Doses?
Nystagmus
What are the SA of Thiordazine at above Reccomended Doses?
Pigmentary Retinopathy
Which Drugs should not be used to dilate the pupil?
Atropine or Scopolamine
