Drugs And CHD

Question 0

The pain felt with angina pectorals results from cardiac ischaemia, true or false

Answer 0

True

Question 1

Nitro vasodilator only dilate arteries, true or false

Answer 1

False

Question 2

An ideal ‘super pill’ proposed to reduce heart attack risks would contain paracetamol, a station and anti hypertensive, true or false

Answer 2

False

Question 3

Dizziness when rising from a sitting position to standing is a common side effect experienced by patients when they have been taking GTN, true or false

Answer 3

True

Question 4

The throbbing/pounding headache often seen as a side effect of GTN is due to increased cerebral blood flow, true or false

Answer 4

False

Question 5

Nitrovasodilators are metabolised to produce nitrous oxide, true or false

Answer 5

False, produces nitric oxide

Question 6

Statins cause a dose-dependent reduction in the concentration of total cholesterol and HDL cholesterol

Answer 6

False

Question 7

GTN is rapidly metabolised by the liver

Answer 7

True

Question 8

Caution must be taken when nitrovasodilators are administered to patients taking anti hypertensives and drugs such as sidenafil, true or false

Answer 8

True

Question 9

Statins inhibit the enzyme HMG-COA reductase, true or false

Answer 9

True

Question 10

What can cause a crushing pain in the chest that may radiate to the arm, back or jaw, most commonly on exertion?

Answer 10

Angina pectoris

Question 11

Which way is GTN not administered

1. Sublingual tablet
2. Orally
3. Nasal spray
4. Transdermal patch

Answer 11

Orally

Question 12

Do nitrovasodilators dilate arteries veins or both

Answer 12

Both

Question 13

Where is nitric oxide usually present?

Answer 13

Made by the epithelium in blood vessels

Question 14

What causes the throbbing headache associated with nitrovasodilators

Answer 14

Increased cerebral blood flow

Question 15

Where does NO have the biggest effect?

Answer 15

Large veins

Question 16

Which drugs MOA gives rise to NO in the cell which activates protein kinase G and reduces contractions

Answer 16

Nitrovasodilators GTN

Question 17

True or false, LDL’s cycle cholesterol away from cells and back to the liver for reprocessing

Answer 17

False

Question 18

Which drugs inhibit HMG-CoA reductase

Answer 18

Statins

Question 19

Why is GTN often administered sublingually

Answer 19

To avoid the first pass effect in the liver

Question 20

Why might aspirin cause stomach ulcers

Answer 20

Inhibits COX1 enzyme, decreasing the production of mucous which protects the stomach