Antidepressants And Anxiolytics Flashcards
True or false, phenelzine is an example of a serotonin re uptake inhibitor
False, it is a MAOI
Which of the following is not a type of antidepressant? A. MAOIs B. Benzodiazepines C. Tricyclic drugs D. Lithium
Benzodiazepines
True or false, tricyclic antidepressants such as amitriptyline may cause the following adverse effects; hypertension, weight gain, oedema, sexual dysfunction and sedation?
False, cause sedation and anticholinergic effects (dry mouth, blurred vision, dizziness, headache and constipation)
Lithium carbonate is used as a mood stabiliser for the prophylaxis and treatment of acute mania, true or false
True
True or false, patients with Parkinson’s disease have a deficiency of dopamine in the substantial nigra
True
True or false, some antidepressants work by decreasing the amount of serotonin at receptors
False
True or false, phenobarbital is used as a sedative in patients preparing for surgery
False, thiopental is used in preparation for surgery. Phenobarbital is used in the treatment of insomnia, anxiety and seizures
True or false, diazepam is an example of a benzodiazepine used to treat patients with anxiety seizures
True
True or false, the two enzymes involved in dopamine metabolism are monoamine oxidase and catechol-o-methyl transferase
True
True or false, 5HT (2A) receptors are found in the frontal and temporal cortices where they are involved in cognition, perception and mood
True
True or false, Y amino butyric acid (GABA) is the major inhibitory neurotransmitter in the brain
True
Clozapine is an example of an atypical antipsychotic drug, true or false
True
True or false, patients taking MAOIs should avoid foods that are rich in tryptophan
False, should avoid foods high in tyramine
True or false, tricyclic antidepressants such as desipramine and imipramine affect acetylcholine re uptake
False, they inhibit the re uptake if serotonin and noradrenaline
GABA binds to GABA receptors in the brain and causes a decrease in chloride permeability, true or false
False, GABA binds to GABA receptors and INCREASES chloride permeability