Antidepressants And Anxiolytics Flashcards

0
Q

True or false, phenelzine is an example of a serotonin re uptake inhibitor

A

False, it is a MAOI

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1
Q
Which of the following is not a type of antidepressant? 
A. MAOIs
B. Benzodiazepines
C. Tricyclic drugs
D. Lithium
A

Benzodiazepines

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2
Q

True or false, tricyclic antidepressants such as amitriptyline may cause the following adverse effects; hypertension, weight gain, oedema, sexual dysfunction and sedation?

A

False, cause sedation and anticholinergic effects (dry mouth, blurred vision, dizziness, headache and constipation)

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3
Q

Lithium carbonate is used as a mood stabiliser for the prophylaxis and treatment of acute mania, true or false

A

True

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4
Q

True or false, patients with Parkinson’s disease have a deficiency of dopamine in the substantial nigra

A

True

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5
Q

True or false, some antidepressants work by decreasing the amount of serotonin at receptors

A

False

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6
Q

True or false, phenobarbital is used as a sedative in patients preparing for surgery

A

False, thiopental is used in preparation for surgery. Phenobarbital is used in the treatment of insomnia, anxiety and seizures

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7
Q

True or false, diazepam is an example of a benzodiazepine used to treat patients with anxiety seizures

A

True

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8
Q

True or false, the two enzymes involved in dopamine metabolism are monoamine oxidase and catechol-o-methyl transferase

A

True

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9
Q

True or false, 5HT (2A) receptors are found in the frontal and temporal cortices where they are involved in cognition, perception and mood

A

True

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10
Q

True or false, Y amino butyric acid (GABA) is the major inhibitory neurotransmitter in the brain

A

True

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11
Q

Clozapine is an example of an atypical antipsychotic drug, true or false

A

True

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12
Q

True or false, patients taking MAOIs should avoid foods that are rich in tryptophan

A

False, should avoid foods high in tyramine

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13
Q

True or false, tricyclic antidepressants such as desipramine and imipramine affect acetylcholine re uptake

A

False, they inhibit the re uptake if serotonin and noradrenaline

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14
Q

GABA binds to GABA receptors in the brain and causes a decrease in chloride permeability, true or false

A

False, GABA binds to GABA receptors and INCREASES chloride permeability

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