Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

NCM 106 > Drugs Affecting the Reproductive System > Flashcards

Drugs Affecting the Reproductive System Flashcards

1
Q

Drugs that affect the female reproductive system

A

estrogen preparation
SERM
Progesterone/progestin
Combination products
Ovarian stimulants
Uterine motility drugs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Estregon preparation drugs

A

estradiol (Estrace)
estrogens, conjugated (Premarin)
estrogens, esterified (Menest)
estropipate (Ogen)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Indications of estrogen preparation

A
  • hormone replacement therapy
  • relief of moderate to severe symptoms of menopause
  • components of combinations contraceptives
  • hypogonadism
  • atrophic vaginitis
  • primary ovarian failure
  • amenorrhea
  • oophorectomy
  • osteoporosis after menopause
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Adverse effects of estrogen preparations

A
  • menstrual irregularities
  • amenorrhea
  • dysmenorrhea
  • nausea/vomiting
  • bloating
  • decreased libido
  • breast swelling
  • edema, hypertension
  • dizziness
  • migraine
  • pancreatitis
  • hepatic adenoma
  • other estrogen dependent cancers
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

estrogen drug interactions:
increased serum level of ________ when given with ______

A

estradiol
grape juice

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

estrogen drug interactions:
increased therapeutic or toxic effects of

A

corticosteroids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

estrogen drug interactions:
increased risk for emboli and thrombi formation when combined with ______

A

nicotine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

estrogen drug interactions:
decreased serum level of estrogen when given in combination with

A

barbiturates, rifampin, tetracyclines, phenytoin, and St. John’s wort

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Selective Estrogen
Receptor Modulators drugs

A

raloxifene (Evista)
toremifene (Fareston)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Indications of SERMs

A

breast cancer
post-menopausal osteoporosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Adverse effects of SERMs

A

GI upset
nausea
vomiting
headache
dizziness
visual changes
mental changes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Stimulations of estrogen receptors at different sites may also cause?

A

hot flashes
skin rash
edema
vaginal bleeding

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Drug interactions (SERMs):
reduces the absorption of raloxifene

A

Cholestyramine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Drug interactions (SERMs):
may interfere with binding
sites

A

highly protein-bound drugs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

highly protein-bound drugs

A

diazepam (Valium)
ibuprofen (Motrin),
indomethacin (Indocin)
naproxen (Naprosyn)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Drug interactions (SERMs):
Warfarin taken with _______ may decrease the prothrombin time

A

raloxifene

17
Q

Indications of progesterone/progestin

A

dysfunctional uterine bleeding
endometriosis
acne
premenstrual dysphoric disorder (PMDD)
relief sign and symptoms of menopause
some cancers
contraceptives

18
Q

adverse effects of progesterone

A

headache, skin irritation, perineal pain, abdominal pain,
diminished sex drive, vaginal bleeding, and the ACHES signs

19
Q

Fertility drugs

A

clomipheme (Clomid)
chorionic gonadotropin (Pregnyl)
cetrorelix (Cetrotide)
ganirelix (Antagon)
menotropins (Pergonal)

20
Q

estrogen increases the effects of ______________ and ____________ but decreases the effects of _____________

A

corticosteroids
tricyclic antidepressants
anticoagulants

21
Q

effects of estrogen and progestin are decreased with ___________ and _________

A

phenytoin and barbiturates

22
Q

increases risk for thrombi and emboli

A

smoking

23
Q

increases the effects of estrogen

A

grapefruit

24
Q

are desirable when vaginal delivery is in the best interest of
the woman and the fetus.

A

oxytocic drugs

25
Q
  • stimulate the neuroreceptor sites to cause contraction of the uterine smooth muscles.
  • They also stimulate contraction of the lacteal glands
    which is important to promote milk ejection.
A

oxytocics

26
Q

indication of oxytocic drugs

A

-induce uterine contraction
- promote uterine involution
-prevent and treat postpartum and postabortion uterine atony and hemorrhage
- stimulate milk ejection
- induce therapeutic abortion

27
Q

Oxytocics drugs

A

ergonovine (Ergotrate)
methylergonovine (Methergine)
oxytocin (Syntocinon)

28
Q

used to treat infertility in women with functioning
ovaries whose partners are fertile.

A

Clomiphenes

29
Q

are used to
stimulate spermatogenesis in men with low sperm counts and otherwise normally
functioning testes.

A

menotropin

30
Q

what form of oxytocic drug is given to promote uterine involution and milk letdown?

A

oral

31
Q

adverse effects of oxytocics

A

abdominal cramping, uterine rupture, uterine hypertonicity,
decreased FHT, arrhythmia (mother and fetus), water intoxication, ergotism

32
Q

contraindications of oxytocics

A

1st stage of
labor, malpresentation and CPD (cephalopelvic disproportion, severe PIH, previous CS, CV disorders

NCM 106 (14 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions