Drugs acting on Prolactin

Question 1

Which hormone regulates the release of Prolactin?

Answer 1

Thyrotropin- Releasing Hormone in Hypothalamus

Question 2

Which neurotransmitter inhibits the release of prolactin from pituitary gland?

Answer 2

Dopamine

Question 3

Dopamine binds to which receptors in the pituitary and inhibit prolactin?

Answer 3

D2 receptors

Question 4

What are conditions which results in excessive secretion of prolactin?

Answer 4

Infertility & Galactorrhea

Question 5

Which condition refers to secretion of milk from breast in non-breastfeeding woman?

Answer 5

Galactorrhea

Question 6

Name a dopamine receptor antagonist which is used in the treatment to increase secretion of prolactin?

Answer 6

Metoclopramide

Question 7

Name drugs that are used as dopamine receptor agonist which decrease prolactin secretion?

Answer 7

Bromocriptine, Cabergoline

Question 8

What is the condition which is associated with galactorrhea and hypogonadism?

Answer 8

Hyperprolactinemia

Question 9

What are the conditions which are resolved when dopamine receptor agonists are used in treatment?

Answer 9

Hyperprolactinemia & Pituitary microadenomas