Drugs Acting on Growth Hormone Flashcards
What is the other name of Growth Hormone?
Somatotropin
What is the hunger hormone in the body?
Ghrelin
Which cells secrete Ghrelin?
Stomach cells
What effect does Growth Hormone has on fat cells?
Breakdown of Triglycerides
What action does growth hormone has on liver?
Secretion of Insulin like Growth Factor (Somatomedins)
What effect does Somatomedins have on our body?
Stimulate proliferation of cartilage cells that results in bone and muscle growth
What is the treatment used in Dwarfism or Growth retardation?
Synthetic Somatotropin
What is the treatment used in growth failure & severe IGF-1 deficiency?
Mecasermin (Recombinant Human IGF-1 product)
In what other conditions Somatotropin is give?
HIV with Cachexia (bone and muscle loss)
In what conditions is the Somatotropin containdicated?
Closed epiphyses in pediatrics, patients with diabetic retinopathy, obese patients with Prader Willi Syndrome
What is a genetic disorder that causes obesity, intellectual disability and short of height?
Prader Willi Syndrome