Drugs Acting on Growth Hormone Flashcards

1
Q

What is the other name of Growth Hormone?

A

Somatotropin

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2
Q

What is the hunger hormone in the body?

A

Ghrelin

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3
Q

Which cells secrete Ghrelin?

A

Stomach cells

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4
Q

What effect does Growth Hormone has on fat cells?

A

Breakdown of Triglycerides

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5
Q

What action does growth hormone has on liver?

A

Secretion of Insulin like Growth Factor (Somatomedins)

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6
Q

What effect does Somatomedins have on our body?

A

Stimulate proliferation of cartilage cells that results in bone and muscle growth

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7
Q

What is the treatment used in Dwarfism or Growth retardation?

A

Synthetic Somatotropin

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8
Q

What is the treatment used in growth failure & severe IGF-1 deficiency?

A

Mecasermin (Recombinant Human IGF-1 product)

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9
Q

In what other conditions Somatotropin is give?

A

HIV with Cachexia (bone and muscle loss)

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10
Q

In what conditions is the Somatotropin containdicated?

A

Closed epiphyses in pediatrics, patients with diabetic retinopathy, obese patients with Prader Willi Syndrome

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11
Q

What is a genetic disorder that causes obesity, intellectual disability and short of height?

A

Prader Willi Syndrome

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