Drugs Flashcards
What is the mode of action of topical corticosteroids?
Vasoconstrictive
Anti-inflammatory
Antiproliferative
In what conditions are topical steroids used?
Eczema
Psoriasis
Lichen planus
Keloid scars
Side effects of topical steroids
Thinning of the skin Purpura Stretch marks Steroid rosacea Perioral dermatitis Fixed telangectasia
Examples of antiseptics
Povidone iodine
Chlorhexidine
Triclosan
Hydrogen peroxide
Clinical uses of antiseptics
Recurrent infections
Antibiotic resistance
Wound irrigation
What conditions can topical antibiotics be used in?
Acne
Rosacea
Impetigo
Infected eczema
Which topical antibiotics are effective in acne?
Clindamycin
Erythromycin
Tetracycline
Which topical antibiotic is most effect for rosacea?
Metronidazole
Which topical antibiotics are used for impetigo?
Mupirocin
Fusidic acid
Which skin conditions are given oral rather than topical antiviral?
Eczema herpeticum Herpes zoster (shingles)
What topical treatment is given for candida?
Antiyeast (e.g. Nystatin, clotrimazole)
What topical treatment is give for ringworm?
Antifungal (e.g. clotrimazole, terbinafine cream)
Examples of antipuritics
Menthol
Capsaicin
Camphor/phenol
In what conditions are keratolytics used?
Viral warts
Hyperkeratotic eczema & psoriasis
Corns & calluses
Example of keratolytic
Scalicylic acid
What other treatments can emollients be paired with to treat psoriasis?
Coal tar Vit D analogues Keratolytic Topical steroid Dithranol
What is iquimod?
An immune response modulator (anti-viral, anti-tumour effects)
What is imiquimod used to treat?
Genital warts
Superficial BCC
Examples of calcineurin inhibitors
Tacrolimus
Pimecrolimus
What skin conditions can calicneurin inhibitors be used to treat?
Atopic eczema (topical)
What is the purpose of emollients?
To enhance rehydration of epidermis
First line management scabies
Permethin
First line boy with mild acne
Topical retinoid or benzoyl oeroxide
What is the singlemost important barrier to drug penetration?
Stratum corneum
