Definitions Flashcards
What is gastrulation?
Cellular organisation into germ layers in days 7-10 of early foetal development
What are Blaschko’s lines?
Developmental growth pattern of skin (not following vessels nerves or lymphatics
What is vitiligo?
Autoimmune disease with loss of melanocytes
What is Nelson’s syndrome?
Melanin stimulating hormone is produced in excess by the pituitary
What is a malignant melanoma?
A tumour of the melanocyte cell line
What is Alopecia areata?
Autoimmune hair loss
What are Melanocytes?
Pigment producing cells from neural crest
What is hyperkeratosis?
Increased thickness of the keratinlayer
What is parakeratosis?
Persistance of nuclei in the keratin layer
What is acanthosis?
Increased thickness of epidermis
What is papillomatosis?
Irregular epithelial thickening
What is spongiosis?
Oedema between keratinocytes
What is inflammtory cell infltrate?
Acute or chronic lymphocytes and/or neutrophils