Dermatitis Flashcards

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1
Q

Features of the acute phases of dermatitis

A
Papulovesicular
Red (erythematous) lesions 
Oedema (spongiosis) 
Ooze of scaling & crusting 
Itchy
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2
Q

Chronic effects of eczema

A

Thickening (lichenification)
Elevated plaques
Increased scallijg

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3
Q

What type of reaction is contact allergic dermatitis?

A

Delayed (Type IV) hypersensitivity reaction

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4
Q

What type of reaction is drug related dermatitis?

A

Type I or IV hypersensitivity reaction

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5
Q

Immunopathology of contact allergic dermatitis

A

Langerhans cells in the epidermis process antigen
Processed antigen is presented to Th cells in dermis
Sensitised Th celks migrate into lymphatics and then to regional lymph nodes where antigen presentation is amplified
On subsequent antigen challenge specifically sensitised T cells proliferate and migrate to and infiltrate skin

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6
Q

How can specific substances causing allergic contact dermatitis be identified?

A

Patch testing

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7
Q

What is nappy rash?

A

Irritant contact dermatitis to urine

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8
Q

What is thenmost important gene in atopic dermatitis?

A

Filaggrin gene

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9
Q

Clinical features of atopic eczema

A
Pruritis (sleep disturbance)
Ill-defined erythema & scaling 
Generalised dry skin 
Flexural distribution 
Associated with other atopic disease
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10
Q

What does crusting of eczema usually indicate?

A

Staph aureus infection

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11
Q

Diagnostic criteria for atopic eczema

A

Itching plus 3 or more
- visible flexural rash
- history of flexural rash (cheeks & extensors in infants)
Personal history of atopy ( or 1st degree relative if

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12
Q

What is the difference between dermatitis & eczema

A

They are the same thing

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13
Q

Treatment of atopic eczema

A
EMOLLIENTS
Avoid irritants 
Topical steroids 
Phototherapy 
Systemic immunosuppresants
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14
Q

What causes eczema herpecticum?

A

Eczema infected with herpes simplex virus

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15
Q

Description of lesions of eczema herpecticum

A

Monomorphic punched-out lesions

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16
Q

What is usually seen clinically in patients with photosensitive eczema?

A

Cut off at collar

17
Q

What is stasis eczema often secondary to?

A

Hydrostatic pressure
Oedema
Red cell extravasation

18
Q

Where does seborrhoeic eczema affect?

A

Scalp
Face
Chest

19
Q

Where does pompholyx eczema affect?

A

Hands & feet

20
Q

What conditions is seborrhoeic dermatitis associated with?

A

Parkinsons disease

HIV