Drugs

Question 1

ACEi

Answer 1

-pril
HTN, heart failure
S/E: cough, headache, kyperkalaemia
C/I: renal artery stenosis, pregnancy

Question 2

ARB

Answer 2

-sartan

Same as ACEi but no cough

Question 3

Beta-blockers

Answer 3

-olol
Angina, post-MI, arrhythmias, clinically stable heart failure
S/E: bronchoconstriction, AV block, claudication, impotence, depression, sedation, masks hypoglycaemia
C/I: uncontrolled heart failure, diabetes, asthma

Question 4

Calcium-channel blockers

Answer 4

Dihydropyridines (-pine) - peripheral
Non-dihydropyridines (-amil) - cardiac
Angina, tachyarrhythmias
S/E: cardiac depression, bradycardia, flushing, oedema, dizziness, headache, constipation, nausea
C/I: heart failure

Question 5

Thiazides

Answer 5

Mild-moderate HTN, oedema, heart failure
S/E: hypokalaemia, hyperuricaemia, hypercholesterolaemia, hyperglycaemia
C/I: diabetes, gout

Question 6

Spironolactone

Answer 6

Potassium sparing diuretic

CCF

Question 7

Amiodarone

Answer 7

Arrhythmias - rhythm control
Increases QT interval and prolongs action potential
S/E: interstitial lung disease, thyroid dysfunction, abnormal liver enzymes

Question 8

Warfarin

Answer 8

Blocks factors II, VII, IX, X, protein C and protein S

Question 9

Heparin

Answer 9

Binds to and activates antithrombin III, which inactivates factor Xa