Drug Treatments For OCD Flashcards

1
Q

What are SSRI drugs?

A

Selective Serotonin Reuptake Inhibitors

SSRIs increase serotonin levels at the synapse by blocking its reuptake.

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2
Q

What effect do SSRIs have on serotonin?

A

They increase serotonin levels at the synapse by blocking its reuptake

This leads to improved mood and emotion regulation.

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3
Q

How do SSRIs affect anxiety and compulsions?

A

They improve emotion regulation and reduce anxiety, thus reducing the need to complete compulsions

This is due to the increased presence of serotonin in the synapse.

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4
Q

What is the role of GABA in neurotransmission?

A

GABA binds to receptor cells to block the binding of certain neurotransmitters

This action helps slow down signals in the nervous system.

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5
Q

What is the primary function of GABA?

A

To inhibit neurotransmitter activity

GABA helps reduce anxiety by slowing down neural signals.

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6
Q

Fill in the blank: SSRIs help to _______ serotonin levels at the synapse.

A

increase

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7
Q

True or False: SSRIs decrease serotonin levels in the synapse.

A

False

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8
Q

What neurotransmitter is primarily involved in mood regulation?

A

Serotonin

Increased serotonin levels are associated with improved mood.

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9
Q

What is the effect of GABA on the nervous system?

A

It reduces anxiety by inhibiting certain signals

GABA is crucial for calming the nervous system.

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10
Q

What happens to serotonin when SSRIs are administered?

A

Serotonin remains in the synapse, leading to increased levels

This is because SSRIs block the reuptake of serotonin.

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11
Q

What is the primary method used to evaluate the effectiveness of drug treatments for OCD?

A

Randomised control trial

This method compares the effectiveness of the drug versus a placebo.

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12
Q

What did Soomro et al. (2008) find regarding the effectiveness of SSRIs for OCD?

A

SSRIs were more effective than placebos in reducing OCD symptoms up to three months after treatment

This was based on a review of 17 studies.

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13
Q

What is a limitation of the studies evaluating drug treatments for OCD mentioned by Koran et al. (2007)?

A

Most studies only have a duration of three to four months

This results in a lack of long-term data.

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14
Q

What percentage reduction in OCD symptoms do drug treatments potentially achieve in the short term?

A

40-60%

This indicates the effectiveness of medication in treating OCD symptoms.

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15
Q

What is one of the main appeals of using drug therapy for OCD?

A

Requires little effort and time from the user

Compared to therapies like CBT which require regular meetings.

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16
Q

How do drug therapies compare in cost to psychological treatments for OCD?

A

Drug therapies are cheaper and require less monitoring

This makes them more appealing to healthcare providers.

17
Q

What is the ‘Dodo Bird effect’ in the context of drug therapy?

A

The idea that simply talking with a doctor may help

This effect suggests that therapeutic interactions can provide benefits.

18
Q

Fill in the blank: Drug treatments for OCD are more effective because they are _______ and _______.

A

cheap and easy

This reduces the need for expensive long-term therapy.

19
Q

What is a criticism of drug therapies for OCD regarding patient compliance?

A

High relapse rates if patients forget or stop taking the drugs

This can lead to severe intrusive thoughts and potential suicide.

20
Q

What are common side effects of SSRIs?

A

Nausea, headache, insomnia

SSRIs are selective serotonin reuptake inhibitors commonly prescribed for OCD.

21
Q

Why are tricyclic antidepressants used only when SSRIs are ineffective?

A

They tend to have more severe side effects

Examples of side effects include hallucinations and irregular heartbeat.

22
Q

What are potential side effects of benzodiazepines (BZs)?

A

Increased aggressiveness, long-term memory impairment, addiction

BZs are often prescribed for anxiety but have significant risks.

23
Q

What is the recommended duration for using benzodiazepines?

A

A maximum of four weeks

This recommendation aims to mitigate the risk of addiction.

24
Q

What is a weakness of drug treatments for OCD?

A

Negative side effects of SSRIs and BZs

These side effects can lead patients to stop taking the medication.

25
Q

What is a criticism of drug treatments for OCD despite their effectiveness?

A

They do not provide a lasting cure

Patients often relapse within weeks if medications are stopped.

26
Q

What alternative treatment is suggested to be more effective than drug therapy for OCD?

A

Cognitive Behavioral Therapy (CBT)

CBT helps patients learn coping strategies for their symptoms.

27
Q

How does CBT help OCD patients?

A

Gradually introduces patients to triggering objects/situations

This technique is similar to systematic desensitization.

28
Q

What is a strength of CBT compared to drug treatments?

A

It provides long-term coping mechanisms

Unlike drugs, which can only prevent symptoms short-term.

29
Q

What is a criticism of CBT as a treatment for OCD?

A

More expensive and time-consuming than drugs

This can decrease patient commitment to therapy.

30
Q

True or False: SSRIs are the only effective treatment for OCD.

A

False

Other treatments like CBT are also effective.