DRUG TREATMENT: CARDIAC & CIRCULATORY Flashcards

1
Q

Upper number, maximum pressure blood obtains, exact moment heart has finished contracting.

A

Systolic blood pressure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Lower number, lowest pressure blood reaches in circulatory system, occurs before heart contracts.

A

Diastolic blood pressure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

________ act on blood pressure by lowering the fluid volume in the circulatory system.

A

Diuretics

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Which of the following diuretics are less potent than loop diuretics?

a) Potassium sparing diuretics
b) Thiazide diuretics

A

b) Thiazide diuretics

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Which of the following diuretics has a unique side effect of causing tinnitus at very high dosing levels and is the most powerful diuretic?

a) Potassium sparing diuretics
b) Thiazide diuretics
c) Loop diuretics

A

c) Loop diuretics

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Which of the following diuretics can limit the loss of potassium?

a) Potassium sparing diuretics
b) Thiazide diuretics
c) Loop diuretics

A

a) Potassium sparing diuretics

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

When speaking of blood pressure control, we are concerned with beta _ receptors of the heart.

A

1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

When speaking of keeping lung passages dilated, we are concerned with beta _ receptors of the lungs.

A

2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

When a beta 1 receptor is triggered, which of the following is true?

a) if blocked, heart rate and blood pressure decrease
b) if unblocked, heart rate and blood pressure increase
c) if unblocked, heart rate and blood pressure decrease
d) if blocked, heart rate and blood pressure increase

A

a) if blocked, heart rate and blood pressure decrease

b) if unblocked, heart rate and blood pressure increase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

True or False

At high doses, newer beta blockers that have a specificity for beta 1 receptors will have no effect on beta 2.

A

False

They will have some effect on beta 2.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Who are the two groups of patients that should probably not receive beta blockers?

A

Asthmatics and diabetics.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

One natural product that can trigger vasoconstriction, thereby raising blood pressure is:

A

Angiotensin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Which of the following is not a potent vasoconstrictor?

a) Angiotensin I
b) Angiotensin II

A

a) Angiotensin I

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Which of the following must be transformed to become a powerful vasoconstrictor?

a) Angiotensin I
b) Angiotensin II

A

b) Angiotensin II

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

The enzyme that transforms Angiotensin I to Angiotensin II is called:

A

Angiotensin Converting Enzyme (ACE)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Which of the following block the receptor which Angiotensin II binds to, blocking its action?

a) Angiotensin Converting Enzyme (ACE)
b) Antagonist Converting Enzyme (ACE)
c) Angiotensin Receptor Agonists (ARA)
d) Angiotensin Receptor Antagonists (ARA)

A

d) Angiotensin Receptor Antagonists (ARA)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

A chronic, dry, hacking cough is a unique side effect of:

A

ACE inhibitor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Which chemical is shuttled into and out of the cell in response to muscle contraction needs?

a) Potassium
b) Sodium
c) Chlorine
d) Calcium

A

d) Calcium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Blocking which chemical channel can slow the electrical transmission of heart impulses?

a) Chlorine
b) Calcium
c) Sodium
d) Potassium

A

b) Calcium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Name the receptors that are found in the central and periphery nervous systems.

A

Alpha receptors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Stimulating which receptor produces an excitatory function and initiates an effect?

a) Alpha II
b) Alpha I

A

b) Alpha I

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Stimulating which receptor has in inhibitory effect and stops a process from occurring?

a) Alpha II
b) Alpha I

A

a) Alpha II

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

When Alpha I receptors are stimulated, smooth muscle of the vessel is ________ , ________ the opening for the blood to flow through.

a) dilated, narrowing
b) dilated, widening
c) constricted, narrowing
d) constricted, widening

A

c) constricted, narrowing

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

If vessels are narrowed, blood pressure:

a) goes up
b) goes down
c) stays the same

A

a) goes up

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

Alpha 1 Blockers decrease blood pressure by:

a) blocking Alpha 2 receptors, stopping the constriction of vessels.
b) blocking Alpha 1 receptors, stopping the constriction of vessels.
c) blocking Alpha 1 receptors, stopping the dilation of vessels.
d) blocking Alpha 2 receptors, stopping the dilation of vessels.

A

b) blocking Alpha 1 receptors, stopping the constriction of vessels.

26
Q

A concern with alpha blockers such as ________ is _____ ____ ________.

A

Prazosin; first dose syncope.

27
Q

What should a patient taking Prazosin do when taking the first dose?

A

Take it in bed

28
Q

Stimulating Alpha 2 receptors:

a) inhibits constriction of the blood vessels, decreasing BP
b) inhibits dilation of the blood vessels, decreasing BP
c) inhibits dilation of the blood vessels, increasing BP
d) inhibits constriction of the blood vessels, increasing BP

A

a) inhibits constriction of the blood vessels, decreasing BP

29
Q

When Alpha 2 receptors are stimulated, the brain stops initiation of the message to the body to ________ blood vessels.

a) lengthen
b) widen
c) dilate
d) constrict

A

d) constrict

30
Q

Angina is caused by:

A

lack of oxygen to the heart

31
Q

Name the 3 main classes of drug used to treat angina.

A

Nitrates, Beta Blockers, and Calcium Channel Blockers

32
Q

Which of the following increases the amount of oxygen to the heart?

a) Nitrates
b) Beta Blockers
c) Calcium Channel Blockers

A

a) Nitrates

33
Q

Which of the following decreases the heart’s need for oxygen?

a) Nitrates
b) Beta Blockers
c) Calcium Channel Blockers

A

b) Beta Blockers

34
Q

A condition where the heart can no longer pump a sufficient amount of blood to the body.

A

Congestive Heart Failure (CHF)

35
Q

Drug classes that can ease the workload of the heart include:

A

Diuretics, ACE inhibitors, and Beta blockers.

36
Q

Drugs that cause an increase in cardiac output by increasing the force of the heart contraction.

A

Inotropic drugs

37
Q

Condition of abnormally high cholesterol and/or triglyceride levels in the body.

A

Hyperlipidemia

38
Q

____ ____ __________ act by binding the bile acids produced by the liver in the intestines and block the absorption of fats (lipids) into the body.

A

Bile acid sequestrants

39
Q

Adverse effects with bile sequestrants include deficiencies of fat soluble vitamins (A, D, E, K) and :

a) constipation
b) abdominal pain
c) nausea
d) all of the above
e) only a & c

A

d) all of the above

40
Q

Niacin is a B vitamin that is used to increase the ____ cholesterol (___) in the bloodstream.

A

good; HDL

41
Q

The ____ cholesterol (___) helps clear the bloodstream of the ___ cholesterol (___).

A

good, HDL

bad, LDL

42
Q

True or False

A proper ratio of good to bad cholesterol is just as important as total cholesterol levels.

A

True

43
Q

Niacin is often formulated into ________ release products to minimize flushing of the face.

A

sustained

44
Q

These work to inhibit the production of triglycerides and raise the level of good cholesterol (HDL).

A

Fibric Acid Derivatives

45
Q

Common side effects for which class of drug include changes in liver enzymes, nausea, rash, and respiratory problems.

A

Fibric Acid Derivatives

46
Q

Which drug class works by inhibiting an enzyme needed in the production of cholesterol in the body?

A

Statins

47
Q

What is the name of the enzyme needed in the production of cholesterol in the body?

A

HMG-CoA reductase enzyme

48
Q

Common side effect for which class of drug include muscles and joint aches, nausea, diarrhea, and constipation.

A

Statins

49
Q

Which one of the following would be used for treating a clotting disorder?

a) Adalat CC
b) Colestid
c) Niacin
d) Pradaxa

A

d) Pradaxa

50
Q

Which one of the following would be used for inhibiting the production of triglycerides and raise HDL level?

a) Cardura XL
b) Betapace
c) Tricor
d) Procardia XL

A

c) Tricor

51
Q

Which one of the following would be used as a Bile Acid Sequestrant?

a) Zestril
b) Welchol
c) Xarelto
d) Verelan

A

b) Welchol

52
Q

Which one of the following would be used for by increasing cardiac output and heart contraction?

a) Lanoxin
b) Lopressor
c) Coumadin
d) Cardizem CD

A

a) Lanoxin

53
Q

Which one of the following would be used as a vasodilator?

a) Niaspan
b) Imdur
c) Questran
d) Heparin

A

b) Imdur

54
Q

Which one of the following would stimulate alpha 2 receptors and is a central acting drug?

a) Nitrodur
b) Dobutamine
c) Catapres
d) Lipitor

A

c) Catapres

55
Q

Which one of the following is an alpha 1 receptor blocker?

a) Zocor
b) Aldomet
c) Digitek
d) Hytrin

A

d) Hytrin

56
Q

Which one of the following has an affinity to act on the heart or in the peripheral blood vessels?

a) Nitro-BID
b) Mevacor
c) Norvasc
d) Atromid-S

A

c) Norvasc

57
Q

Which one of the following blocks the receptors which angiotensin II binds to?

a) Calen
b) Cozaar
c) Eliquis
d) Lopid

A

b) Cozaar

58
Q

Which one of the following is an ACE Inhibitor?

a) Vasotec
b) Diovan
c) Prazosin
d) Procardia

A

a) Vasotec

59
Q

Which one of the following blocks beta receptors eliminating increase of HR and BP?

a) Prinvil
b) Inderal
c) Tiazac
d) Lescol

A

b) Inderal

60
Q

Which one of the following is a Potassium Sparring Diuretic?

a) Esidrix
b) Lozol
c) Aldactone
d) Demadex

A

c) Aldactone

61
Q

Which one of the following is a Loop Diuretic and can cause tinnitus at very high dose levels?

a) Chlorthalidone
b) Lozol
c) Microzide
d) Lasix

A

d) Lasix

62
Q

Which one of the following is a Thiazide Diuretic?

a) Zaroxolyn
b) Bumex
c) Dyrenium
d) Amiloride

A

a) Zaroxolyn