Drug Therapy with Corticosteroids Ch 15

Question 1

Addison’s disease

Answer 1

primary adrenocortical insufficiency with inadequate production of cortisol and aldosterone

Question 2

Addisonian crisis

Answer 2

condition that mimics hypovolemic and septic shock; also known as adrenocortical insufficiency

Question 3

Aldosterone

Answer 3

mineralocorticoid hormone secreted by the adrenal cortex to increase sodium reabsorption by the kidneys and indirectly regulate blood levels of potassium, sodium, and bicarbonate; also regulates pH, blood volume, and blood pressure

Question 4

Corticosteroid

Answer 4

steroid hormones produced by the adrenal cortex; examples include androgens, glucocorticoids, and mineralocorticoids

Question 5

Cortisol

Answer 5

the main glucocorticoid secreted as part of the body’s response to stress

Question 6

Cushing’s disease

Answer 6

adrenocortical hyperfunction; may result from excessive corticotropin or primary adrenal tumor

Question 7

Glucocorticoid

Answer 7

adrenal cortical hormone that protects the body against stress and affects protein and carbohydrate metabolism

Question 8

Immunosuppression

Answer 8

suppression of the immune system

Question 9

Mineralocorticoid

Answer 9

steroid hormone released by the adrenal cortex to promote sodium and water retention and potassium excretion

Question 10

Negative feedback mechanism

Answer 10

when the output of a system affects the stimulus for the system (e.g., hormone secretion produces an effect that shuts off the stimulus for further hormone secretion)

Question 11

Steroid

Answer 11

lipid-soluble hormone produced by the gonadal organs or the adrenal cortex