Drug Therapy to Suppress Immunity Ch 11

Question 1

Autoantigens

Answer 1

protein complexes on a person’s own tissue that stimulate an abnormal immune reaction

Question 2

Autoimmune disorders

Answer 2

conditions associated with an abnormal immune response to self-antigens (autoantigens) on body tissue, resulting in ongoing inflammation and damage to body tissues

Question 3

Cytotoxic

Answer 3

causing cell death

Question 4

Graft rejection reaction

Answer 4

activated immunological response by the recipient to graft donor organ cells resulting in graft tissue damage and loss of graft organ function

Question 5

Graft-versus-host disease

Answer 5

complication of bone marrow or stem cell transportation where activated T cells in donor bone marrow attack host tissues producing inflammatory changes in the skin, liver, and gastrointestinal tract, also can occur infrequently with a blood transfusion

Question 6

Immunosuppression

Answer 6

suppression of the immune system

Question 7

Monoclonal antibody

Answer 7

immunoglobulin therapeutically replicated in laboratory cells to react with a specific cell antigen altering the immune response to that antigen

Question 8

Murine antibodies

Answer 8

immunoglobulins created in mouse cells for use as therapeutic treatment for human diseases

Question 9

Polyclonal antibody

Answer 9

mixtures of antibodies (IgA, IgD, IgE, IgG, and IgM) produced by several clones of B lymphocytes