Drug Therapy for Coagulation Disorders Ch 7 E2

Question 1

Anticoagulants

Answer 1

drugs that prevent formation of new clots and extension of clots already present; do not dissolve formed clots

Question 2

Antiplatelets

Answer 2

drugs that prevent one or more steps in the prothrombotic activity of platelets

Question 3

Embolus

Answer 3

object that migrates through the circulation until it lodges in a blood vessel, causing occlusion; may be a thrombus, fat, air, amniotic fluid, a bit of tissue, or bacterial debris

Question 4

Essential thrombocythemia

Answer 4

chronic blood disorder characterized by the overproduction of platelets by megakaryocytes in the absence of another cause

Question 5

Fibrinolysin

Answer 5

enzyme that breaks down the fibrin meshwork that stabilizes blood clots; also referred to as plasmin

Question 6

Hemostasis

Answer 6

prevention or stoppage of blood loss from an injured blood vessel and is the process that maintains the integrity of the vascular compartment

Question 7

Heparin-induced thrombocytopenia (HIT

Answer 7

immune-mediated prothrombotic reaction resulting in a decrease in platelet count associated with heparin administration in patients with detectable HIT antibodies

Question 8

Plasmin

Answer 8

enzyme that breaks down the fibrin meshwork that stabilizes blood clots; also referred to as fibrinolysin

Question 9

Plasminogen

Answer 9

inactive protein found in many body tissues and fluids

Question 10

Prothrombotic reaction

Answer 10

adverse effect that leads to thrombogenesis

Question 11

Thrombogenesis

Answer 11

formation of a blood clot

Question 12

Thrombolysis

Answer 12

breakdown or dissolution of blood clots

Question 13

Thrombolytics

Answer 13

drugs that dissolve blood clots

Question 14

Thrombosis

Answer 14

formation of a blood clot

Question 15

Thrombus

Answer 15

blood clot