Drug Therapy for Heart Failure Ch 24

Question 1

Catecholamines

Answer 1

active amines (e.g., epinephrine, norepinephrine, dopamine) that have an effect on the cardiovascular system

Question 2

Decompensation

Answer 2

the inability of the heart to adequately circulate oxygenated blood to the body’s vital organs

Question 3

Diastolic dysfunction

Answer 3

impaired relaxation and filling of the ventricles during diastole

Question 4

Digitalis toxicity

Answer 4

an accumulation of digitalis in the body that leads to nausea, vomiting, and atrial tachycardia

Question 5

Digitalization

Answer 5

the administration of a loading dose of digoxin (Lanoxin) to achieve a therapeutic blood level of the medication more rapidly

Question 6

Endothelin

Answer 6

a peptide that raises blood pressure, constricts blood vessels, and contributes to the onset of heart failure

Question 7

Inotropic

Answer 7

related to or influencing the force of myocardial contractility

Question 8

Renin

Answer 8

an enzyme produced by the kidney that divides angiotensinogen to form angiotensin I, which is then changed to angiotensin II to produce vasoconstriction

Question 9

Systolic dysfunction

Answer 9

impaired myocardial contraction during systole

Question 10

Therapeutic index

Answer 10

the blood level of a medication that will produce therapeutic effects

Question 11

Ventricular remodeling

Answer 11

dilatation and hypertrophy of the ventricles in the initial phases of heart failure, causing the ventricle to assume a spherical shape