Drug Therapy for Fluid Volume Excess Flashcards
Anasarca
generalized massive edema
Anuria
no urine output (don’t give this person a diuretic)
Ascites
fluid overload in the abdomen
Edema
General medical term for swelling
Dependent Edema
dependent on the lowest point in the body. Feet and fingers.
Extracellular Fluid
Fluid outside of the cells
Intracellular Fluid
Fluid inside the cell
Renal Physiology
Kidneys, Ureters, Bladder, Urethra
Primary Function of Kidneys
Regulate Volume (how much fluid to get rid of)
Composition of Urine (how many electrolytes we are going to keep)
Regulate pH (How many H+ ions we are going to eliminate)
Eliminating Wastes (medications, diet)
BP Regulation
RAAS System
increases perfusion through the kidneys and makes red blood cells through erythropoietin production
RBC Production effect on BP
Increase
Vitamin D Conversion
maintain strong bones
Amount of Output the Kidney’s receive
receive 25% of cardiac output
Renal Capsule
the fibrous protection around the kidney to protect it because a bunch of blood is flowing through it
Regions of Kidney
Cortex, Medulla, Renal Pelvis
Cortex
we are going to see part of the nephron
Nephron
functional unit of the kidney. One million nephrons in each kidney
Medulla
middle layer that contains the loop of Henle and collecting ducts
Renal Pelvis
takes newly made urine and makes it ready to go to the bladder
Nephron Functions
Glomerular Filtration
Tubular Secretions
Tubular Reabsorption
Glomerular Filtration
filters out things that are good and need to stay in the body (protein, Na, K)
First stop of the blood coming into the kidney
Tubular Secretions
things that are secreted out with your urine
Tubular Reabsorption
things that your body is reabsorbing for you to use again
bowman’s capsule
Blood comes in from the aorta into the glomerulus under high pressure
Under the high pressure, it pushes water, electrolytes, and other solutes out into bowman’s capsule which is like a catchers mitt
Bowman’s capsule pushes it down through the tubules where the urine is made
Glomerular Filtration Rate:
How fast the glomerular is able to filter your blood! The faster the better
125 ml/min is normal
2L of secretion is normal
Conditions requiring Diuretic Agents:
Alterations in renal function (GFR)
Renal
Cardiovascular
Hepatic
Burns
Trauma
Allergies
Inflammatory Reactions
Reasons for Swelling
Increased Capule Permeability
Increased hydrostatic pressure
Decreased Plasma Oncotic Pressure
Decreased Plasma Oncotic Pressure
result from low plasma protein which are responsible for holding on to fluids and keeping them where they should be.
Increased hydrostatic pressure
increase blood volume causing high venous pressure. So much volume on the inside that the body tries to push it to the outside