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PMCOL 343 > drug names-1 > Flashcards

drug names-1 Flashcards

1
Q

botulinum toxin

A

blocks ACh release from vesicles

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2
Q

carbachol

A

choline ester

nicotinic muscarinic

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3
Q

bethanechole

A

choline ester muscarinic

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4
Q

oxotremorine

A

muscarinic agonist

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5
Q

pilocarpine

A

muscarinic agonist

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6
Q

edrophonium

A

anticholinesterase
simple alchohol
reversible theraputic

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7
Q

neostigmine

A

anticholinesterase
ester with ammonium
reversible theraputic

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8
Q

malathion

A

anticholinesterase
organophosphatase
insecticide

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9
Q

soman

A

anticholinesterase
organophosphatase
nerve gas

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10
Q

succinylcholine

A 
nicotinic antagonist (neuromuscular blocker)
paralysis during surgery
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11
Q

D-Tubocurarine

A 
nicotinic antagonist (neuromuscular blocker)
poison darts
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12
Q

α-bungarotoxin

A 
nicotinic antagonist (neuromuscular blocker)
protein in snake venom
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13
Q

atropine

A

muscarinic antagonist

dilate pupils

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14
Q

scopalamine

A

muscarinic antagonist

motion sickness

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15
Q

ipratropium

A

muscarinic antagonist

COPD

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16
Q

isoproterenol

A

β agonist
(ANI & IAN)
Cardiac arrest, AV/heart block

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17
Q

prazosin

A

α1 antagonist
Not as much reflex tachycardia as phentomaine
prevents prostate contraction

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18
Q

yohimbine

A

α2 antagonist

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19
Q

phenylephrine

A

α1 agonist

-nasal decongest, dilate eye

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20
Q

clonidine

A

α2 agonist

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21
Q

dobutamine

A

β1 agonist

Acute heart failure, cardiogenic shock

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22
Q

salbutamol

A

β2 agonist

asthma

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23
Q

phentolamine

A

α antagonist
pheochromocytoma
reflex tachycardia (α2 does negative feedback, so blocking it allows more NA release, unblocked β(heart stimulating))

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24
Q

propranolol + how it works

A

β antagonist

Reduce sympathetic outflow
↓ renin release
Block presynaptic β receptors (reduce NA release)

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25
Q

metoprolol

A

β1 antagonist

lower blood pressure

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26
Q

tyramine

A

displace stored catecholamines from vesicles
metabolized by MAO in liver
indirectly acting sympathomimetic

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27
Q

methamphetamine

A

speed, not amphetamine

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28
Q

methylphenidate

A

amphetamine
release DA/NA in absence of nerve activity
displace stored catecholamines from vesicles
indirectly acting sympathomimetic

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29
Q

timolol

A

β blocker
lower IOP
Reduces secretion of aqueous humor from ciliary bodies

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30
Q

physostigmine

A

Anticholinesterase
lower IOP
Ciliary muscle contraction, ↑ the outflow of aqueous humor

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31
Q

apraclonidine

A

similar to adrenaline effect
Vasoconstrict, ↓ flow to ciliary body, ↓ secretion of aqueous humor
lower IOP

32
Q

anandamide

A

Cannabinoid endogenous ligand, CB1 and CB2 receptors

Lowers IOP by relaxing trabecular network

33
Q

cromolyn

A

Prevent mast cell degranulation + release of inflammatory mediators

34
Q

nedocromil

A

Prevent mast cell degranulation + release of inflammatory mediators

35
Q

diphenhydramine

A

Benadryl, classic H1 antihistamine + sedative

36
Q

dimenhydrinate

A

Gravol - H1 antihistamine for motion sickness

37
Q

loratidine

A

Claritin - H1 antihistamine for seasonal rhinitis

38
Q

cimetidine

A

H2 antagonist for stomach acid

39
Q

ranitidine

A

H2 antagonist for stomach acid

40
Q

theophylline

A

Antagonize adenosine, helps stop bronchoconstriction

41
Q

cocaine

A

Inhibits DA&NA reuptake (uptake 1)
Local anesthetic and hemostatic (limits bleeding & systemic absorption due to vasoconstriction)
indirectly acting sympathomimetic

42
Q

TCAs

A

Inhibit catecholamine reuptake

indirectly acting sympathomimetic

43
Q

motelukast

A

Antagonist to IL-4 - asthma

44
Q

biologics

A

IL-5 antibodies - asthma

45
Q

what is an example of a β1 antagonist

A

Metoprolol

46
Q

what are 2 choline esters that arent hydrolyzed by acetylcholineterase

A

carbachol and bethanechol

47
Q

example of α1 agonist

A

phenylephrine

48
Q

example of α2 agonist

49
Q

what is an example of a β1 agonist

A

dobutamine

50
Q

what is an example of a β2 agonist

A

salbutamol

51
Q

what is an example of a β agonist

A

isoproterenol

52
Q

example of α antagonist

A

phentolamine

53
Q

example of α1 antagonist

54
Q

example of α2 antagonist

55
Q

what is an example of a β antagonist

A

propranolol

56
Q

what is an example of a β1 antagonist

A

metoprolol

57
Q

what are 2 muscarinic agonists

A

oxotremorine

pilocarpine

58
Q

4 anticholinesterases

+ 1 for glaucoma

A

edrophonium
neostigmine
malathion
soman

physostigmine

59
Q

3 nicotinic antagonists

A

Succinylcholine
D-tubocurarine
α-bungarotoxin

60
Q

3 muscarinic antagonists

A

atropine
scopolamine
ipratropium

61
Q

3 directly acting sympathomimetic drugs

A

adrenaline
noradrenaline
isoproterenol

62
Q

3 indirectly acting sympathomimetic drugs

A

amphetamine
tyramine
cocaine
TCAs

63
Q

what inhibits ACh release from vesicles

A

botulinim toxin

64
Q

what β blocker for glaucoma

65
Q

anticholinesterase for glaucoma

A

physostigmine

66
Q

similar to adrenaline for glaucoma

A

apraclonidine

67
Q

cannabinoid ligand, good fo glaucoma

A

anandamide

68
Q

prevents mast cell degranulation (2)

A

cromolyn

nedocril

69
Q

benadryl

A

Diphenhydramine

70
Q

gravol

A

Dimenhydrinate

71
Q

claritin

A

loratidine

72
Q

H2 antagonists

A

cimetidine

ranitidine

73
Q

antagonist to adenosine

A

theophylline caffeine

74
Q

IL-4 antagonist

A

motelukast

75
Q

IL-5 antibodies

PMCOL 343 (31 decks)

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