Drug List Flashcards
What are the ACE inhibitors?
The “-prils” Enalapril, lisinopril, and captopril
What do the ACE inhibitors Enalapril, lisinopril, and captopril do?
Impede the production of Angiotensin II
What does Angiotensin II do?
Vasoconstrictor that stimulates secretion f aldosterone
What are the Angiotensin receptor blockers (ARBs)?
The “-sartans” losartan and irbesartan
What do the Angiotensin receptor blockers (ARBs): the “-sartans”: losartan, irbesartan do?
Selectively block type AT1 angiotensin II receptor
What is a cholinergic muscarinic antagonist?
Atropine
What does the cholinergic-muscarinic antagonist atropine do?
Blocks cholinergic-muscarinic effects of ACh
-also an antiparasympathetic
What are the β-blockers?
The “-olols” metoprolol and atenolol
What do the β-blockers, the “-olols” metoprolol and atenolol do?
Impede the β1-mediated SNS effects
What is a Type L Ca2+ channel antagonist in VSM?
Amlodipine
What does the Type L Ca2+ channel antagonist amlodipine do?
Preferentially blocks type L Ca2+ channels expressed in vascular smooth muscle
Mediate vascular smooth muscle contraction
Type L Ca2+ channels
What are the positive inotropics?
Epinephrine, norepinephrine, and the cardiac glycosides (digoxin)
What do the positive inotropics epinephrine, norepinephrine, and the cardiac glycosides (digoxin) do?
Enhance cardiac contractility (all three) and/or rate (epi and norepi)
What is an example of a loop diuretic
Furosemide
What does the loop diuretic furosemide do?
Impairs Na+, K+, and Cl- reabsorption by the kidneys
What does impairing Na+, K+, and Cl- reabsorption by the kidneys do?
Holds H2O in forming urine and induces diuresis
What is an example of a thiazide diuretic?
Hydrochlorothiazide (HCTZ)
What does the thiazide diuretic Hydrochlorothiazide (HCTZ) do?
Impairs Na+ resorption by the kidneys
What are the calcium channel blockers?
Verapamil and diltiazem
What do the calcium channel blockers verapamil and diltiazem do?
Block cardiac type L channels and delay AV nodal conduction
Are negative inotropins with little effect on non-cardiac type L channels
Verapamil and diltiazem
What are the β2 adrenoreceptor agonists?
Albuterol and salmeterol
A short acting β2 agonist
Albuterol
A long acting β2 agonist
Salmeterol
What do the β2 adrenoreceptor agonists albuterol and salmeterol do?
Promote bronchiolar smooth muscle relaxation
Inhaled glucocorticoid receptor agonist
-an anti-inflammatory
Fluticasone
Which things impair renal Na+ resorption?
Furosemide, HCTZ
Which things would reduce exercise induced tachycardia?
B-blockers
What would increase interval between SA node APs
B-blockers
What could we use for outpatient management of a 26-YO with asthma?
Albuterol, Salmeterol, Fluticasone
