Drug interactions Flashcards
1
Q
What is the interaction between clarithromycin and simvastatin?
A
Muscle aching as clarithromycin interacts with the cytochrome P450 system
2
Q
What is the side effect of prescribing amitriptyline with citalopram?
A
Serotonin syndrome
3
Q
What drugs can lower the seizure threshold of patients taking phenytoin?
A
SSRIs, TCAs, tramadol
4
Q
What drugs can reduce the antiplatelet effect of clopidogrel?
A
Omeprazole and fluoxetine
5
Q
What drug should not be prescribed to a patient on beta blockers?
A
Verapamil
6
Q
How does rifampicin interact with warfarin?
A
Induces cytochrome P450 system which increases metabolism of warfarin, reducing the anticoagulant effects & reducing INR