Antibiotics Flashcards
What are the CURB65 criteria?
Confusion, urea >7, respiratory rate>30, blood pressure <90 systolic, age >65
How do you treat mild/moderate community acquired pneumonia?
Oral amoxicillin (doxycycline if penicillin allergic) for 5 days
How do you treat severe CAP?
IV co-amoxiclav (IV levofloxacin if penicillin allergic) + oral doxycycline for 5 days
How do you treat non-severe hospital acquired pneumonia?
Oral amoxicillin (oral doxycycline if penicillin allergic) for 5 days
How do you treat severe HAP?
IV amoxicillin (IV co-trimoxazole if penicillin allergic) + IV gentamicin for 7 days
What is the step down therapy for severe CAP?
Oral doxycycline
What is the step down therapy for severe HAP?
Oral co-trimoxazole
How do you treat bacterial meningitis?
IV ceftriaxone + IV dexamethasone (benzylpenicillin in community)
How do you treat viral encephalitis?
IV acyclovir
How do you treat meningitis in a patient >60 or immunocompromised?
Add IV amoxicillin to IV ceftriaxone + IV dexamethasone
How do you treat epiglottitis?
IV ceftriaxone
How do you treat subacute endocarditis?
IV amoxicillin + IV gentamicin
How do you treat acute endocarditis?
IV flucloxacillin
How do you treat prosthetic valve endocarditis?
IV vancomycin + IV gentamicin
How do you treat non-severe C.diff infection?
Oral metronidazole for 10 days
How do you treat severe C.diff infection?
Oral vancomycin +/- IV metronidazole for 10 days
How do you treat intra-abdominal sepsis?
IV amoxicillin (IV vancomycin if penicillin allergic) + IV metronidazole + IV gentamicin
What is the step down therapy for intra-abdominal sepsis?
Oral co-trimoxazole + oral metronidazole
How do you treat a UTI in a non-pregnant woman?
Oral nitrofurantoin or oral trimethoprim for 3 days
How do you treat UTI in a pregnant woman?
Do NOT give nitrofurantoin in the 3rd trimester or trimethoprim in the 1st semester
How do you treat a UTI in a man?
Oral nitrofurantoin or oral trimethoprim for 7 days
How do you treat pyelonephritis?
IV amoxicillin (IV co-trimoxazole if penicillin allergic) + IV gentamicin for 7 days
What is the step down therapy for pyelonephritis?
Oral co-trimoxazole
How do you treat gonorrhoea?
IM ceftriaxone
How do you treat chlamydia?
Oral doxycycline for 7 days
How do you treat syphilis?
IM long-acting benzathine penicillin
How do you treat genital herpes?
Oral acyclovir for 5 days
How do you treat bacterial vaginosis or trichomonas vaginalis?
Oral metronidazole for 7 days
How do you treat vaginal thrush?
Clotrimazole pessary or cream +/- oral fluconazole
How do you treat cellulitis, osteomyelitis and septic arthritis?
IV flucloxacillin (oral doxycycline if penicillin allergic)
