Antibiotics Flashcards

1
Q

What are the CURB65 criteria?

A

Confusion, urea >7, respiratory rate>30, blood pressure <90 systolic, age >65

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2
Q

How do you treat mild/moderate community acquired pneumonia?

A

Oral amoxicillin (doxycycline if penicillin allergic) for 5 days

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3
Q

How do you treat severe CAP?

A

IV co-amoxiclav (IV levofloxacin if penicillin allergic) + oral doxycycline for 5 days

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4
Q

How do you treat non-severe hospital acquired pneumonia?

A

Oral amoxicillin (oral doxycycline if penicillin allergic) for 5 days

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5
Q

How do you treat severe HAP?

A

IV amoxicillin (IV co-trimoxazole if penicillin allergic) + IV gentamicin for 7 days

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6
Q

What is the step down therapy for severe CAP?

A

Oral doxycycline

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7
Q

What is the step down therapy for severe HAP?

A

Oral co-trimoxazole

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8
Q

How do you treat bacterial meningitis?

A

IV ceftriaxone + IV dexamethasone (benzylpenicillin in community)

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9
Q

How do you treat viral encephalitis?

A

IV acyclovir

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10
Q

How do you treat meningitis in a patient >60 or immunocompromised?

A

Add IV amoxicillin to IV ceftriaxone + IV dexamethasone

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11
Q

How do you treat epiglottitis?

A

IV ceftriaxone

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12
Q

How do you treat subacute endocarditis?

A

IV amoxicillin + IV gentamicin

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13
Q

How do you treat acute endocarditis?

A

IV flucloxacillin

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14
Q

How do you treat prosthetic valve endocarditis?

A

IV vancomycin + IV gentamicin

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15
Q

How do you treat non-severe C.diff infection?

A

Oral metronidazole for 10 days

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16
Q

How do you treat severe C.diff infection?

A

Oral vancomycin +/- IV metronidazole for 10 days

17
Q

How do you treat intra-abdominal sepsis?

A

IV amoxicillin (IV vancomycin if penicillin allergic) + IV metronidazole + IV gentamicin

18
Q

What is the step down therapy for intra-abdominal sepsis?

A

Oral co-trimoxazole + oral metronidazole

19
Q

How do you treat a UTI in a non-pregnant woman?

A

Oral nitrofurantoin or oral trimethoprim for 3 days

20
Q

How do you treat UTI in a pregnant woman?

A

Do NOT give nitrofurantoin in the 3rd trimester or trimethoprim in the 1st semester

21
Q

How do you treat a UTI in a man?

A

Oral nitrofurantoin or oral trimethoprim for 7 days

22
Q

How do you treat pyelonephritis?

A

IV amoxicillin (IV co-trimoxazole if penicillin allergic) + IV gentamicin for 7 days

23
Q

What is the step down therapy for pyelonephritis?

A

Oral co-trimoxazole

24
Q

How do you treat gonorrhoea?

A

IM ceftriaxone

25
Q

How do you treat chlamydia?

A

Oral doxycycline for 7 days

26
Q

How do you treat syphilis?

A

IM long-acting benzathine penicillin

27
Q

How do you treat genital herpes?

A

Oral acyclovir for 5 days

28
Q

How do you treat bacterial vaginosis or trichomonas vaginalis?

A

Oral metronidazole for 7 days

29
Q

How do you treat vaginal thrush?

A

Clotrimazole pessary or cream +/- oral fluconazole

30
Q

How do you treat cellulitis, osteomyelitis and septic arthritis?

A

IV flucloxacillin (oral doxycycline if penicillin allergic)