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Dermatology > Drug eruptions > Flashcards

Drug eruptions Flashcards

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Dermatology Board Prep flashcards
1
Q

What is toxic epidermal necrolysis

A

Fever
tender erythema affecting more than 30% of the skin surface + mucosal involvement.
It is a cell mediated cytotoxic reaction against epidermal cells by activated lymphocytes and cytokines

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2
Q

What common drugs can cause toxic epidermal necrolysis?

A

Allopurinol
Sulphonamides
Anticonvulsants (phnytoin, carbemazepine, lamotrigine
NSAIDs

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3
Q

What is the treatment for toxin epidermal necrolysis?

A

Stop precipitating drug
Supportive care in ICU
IV immunoglobulin Plasmapheresis

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Dermatology (16 decks)

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