Drug Development Stages

Question 1

Describe what happens in STAGE 1 of drug testing (2 points)

Answer 1

• drugs are tested on human cells and tissues that are grown in a laboratory
• if drug is found to damage cells or doesn’t work it’s not tested further

Question 2

Describe STAGE 2 of drug testing (2 points)

Answer 2

1- drugs that past stage 1 are tested on LIVE ANIMALS

2- a known amount of the substance/drug is given to the animal+ it’s monitored carefully

Question 3

Describe STAGE 3 PHASE 1 of drug testing (3 points)

Answer 3

• drug tested on HEALTHY human volunteers (small scale)

-given very low doses

-monitored for any side effects at low doses when the body is working normally

Question 4

Describe STAGE 3 PHASE 2 of drug testing (3 points)

Answer 4

• tested on patients suffering from the disease (small scale)

-initially given low doses+ monitored for side effects

-patients are given increasing doses to identify the most effective dose with least side effects (optimum dose)

Question 5

Describe STAGE 3 PHASE 3 of drug testing

Answer 5

• testing on more people ( larger scale trial)