Drug Delivery

Question 1

Enteral and parenteral administration differences

Answer 1

Enteral enters through the GI tract, parenteral uses intravenous, or other blood system deliveries.

Question 2

How do anatomical barriers affect drug delivery?

Answer 2

Mucosa and other barriers hinder drug delivery, usually chemically and physiologically.

Question 3

What factors affect the bioavailability of drugs?

Answer 3

Physical state
Stomach interactions
Chemical properties.

Question 4

Inhalational delivery

Answer 4

Aerosols can be used to target bronchial cells.

Question 5

Biotransformation of drugs

Answer 5

The liver converts drugs into water soluble compounds, involving phase 1 and phase 2 interactions.

Question 6

Drug - drug/food interactions

Answer 6

Combinations of drugs and certain foods can result in diminished effects or adverse side effects,

Question 7

Key principle in drug delivery

Answer 7

Overcoming physiological, immunological, and metabolic processes to reach target organ/cells.

Question 8

Routes of drug administration

Answer 8

Oral, inhaled, dermal, sublingual, rectal, intravenous, intramuscular.