Blood toxicity

Question 1

Blood toxicity

Answer 1

Adverse effects of toxins/chemicals on blood in an indirect way via depression of bone marrow or by directly affecting blood cells.

Question 2

Blood poisoning

Answer 2

Not directly caused by a toxin but rather a bacterial infection of the bloodstream.

Question 3

Leukocytes (6)

Answer 3

Neutrophils - Phagocytize bacteria
Eosinophils - Release chemicals to kill parasites
Monocytes - developing macrophages
Macrophages - Phagocytize foreign materials
Basophils - Clots injuries
Natural killer cells - kill cancerous cells

Question 4

Toxicity result on bone marrow

Answer 4

Severely impaired blood cell production in depressed bone marrow.

Question 5

Pancytopenia

Answer 5

All blood cell types are not generated.

Question 6

Anemia

Answer 6

Red blood cells are not generated.

Question 7

Leukopenia

Answer 7

White blood cell types are not generated.

Question 8

Thrombocytopenia

Answer 8

Platelets are not generated.

Question 9

Agents associated with Pancytopenia

Answer 9

Benzene, ionizing radiation, anti-metabolites and alkylating agents.

Question 10

Agents associated with anemia

Answer 10

Methotrexate, chloramphenicol, phenylbutazone.

Question 11

Acute radiation syndrome

Answer 11

Constellation of health effects present 24 hours following ionizing radiation exposure.

Question 12

Hemolysis

Answer 12

Damage or destruction of red blood cells, often caused by cephalosporins, quinidine and high doses of penicllin.

Question 13

Agents associated with thrombocytopenia

Answer 13

Quinine, cistplatin, cyclophosphamide, heparin and gold salts.

Question 14

Anemic hypoxia

Answer 14

Carbon monoxide poisoning, it binds much easier (230x) to hemoglobin leaving the blood and body starved of oxygen when in high levels.