Drug Cards quiz 2 Flashcards

1
Q

Hormone

A

Testerone Gel
Progesterone oral
Estrogens conjugated

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2
Q

Testosterone Gel
Progesterone oral
Estrogens conjugated

A

Androgel, Fortesta, Testim
Prometrium
Premarin

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3
Q

Hormone Indication

A

Testosterone :
deficiency/absence of testosterone
Progesterone:
-Prevention of endometrial hyperplasia in postmenopausal
-Secondary Amenorrhea
Estrogens:
–Vasomotor symtoms w/ menopause
-Female hypogonadism
-Female castration and primary ovarian failure
-Breast cancer
-Prostatic cancer
-Prostastic carcinoma
-Post menopausal osteoporosis

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4
Q

Hormone Doses

A

Testosterone Gel: 50 mg
Progesterone : 200 mg
Estrogen: 1.25 mg

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5
Q

Hormone MOA

A

-Testosterone:
Inhibit/stimulate mRNA transcription
-Progesterone: Increased synthesis of RNA
-Estrogen:stimulate specific RNA and protein synthesis @female sex organs
decrease FSH,LH,

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6
Q

Hormone
Interactions

A

Testosterone : insulin,corticosteroids
Progesterone : ketonazole
Estrogen : rifampin,hydratoins

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7
Q

Hormone
Contradiction

A

Testosterone :cancer, women, children, heart failure
Progesterone: cancer,peanut allergy, pregnancy, thrombophlebitis, liver dysfunction
Estrogen: breast cancer, neoplasia, pregnancy, genital bleeding ,nursing mothers

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8
Q

Hormone
Adverse effects

A

Testosterone :Increased PSA, emotional ,hypertension,Increased hemoglobin
Progesterone: abdominal pain, viral infection, cough,breast pain
Estrogen: alopecia ,hirsutism, abnormal menstrual bleeding, weight changes

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9
Q

Hormone
PC

A

Testosterone: No genital area,
Avoid showering
Monitor: hematocrit,hemoglobin,testosterone,psa,lipid panel,lft
Progesterone: caution when performing activities
Estrogen : discontinue if pregnant

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10
Q

Antibacterial
(TetracyclineAntibiotic)
(Macrolide Antibiotic)

A

Minocycline Hydrochloride

Doxycycline Hyclate

Azithromycin Dihydrate

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11
Q

Minocycline Hydrochloride
Azithromycin Dihydrate
Doxycycline Hyclate

A

Minocin, Dynacin,Solodyn ER
Zithromax, Zmax
Vibramycin, Doryx

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12
Q

Antibacterial
Indications
TetracyclineAntibiotic)
(Macrolide Antibiotic)

A

Syphilis, Gonorrhea, chlamydia/ureaplasma
Minocin : meningitidis
Doryx : Malaria
Exception
Zmax: otitis media, pneumonia, ,ulcer

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13
Q

Antibacterial
TetracyclineAntibiotic)
(Macrolide Antibiotic)
MOA

A

competitively binding to 30S ribosomal subunits in bacteria

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14
Q

Antibacterial
Interactions
TetracyclineAntibiotic)
(Macrolide Antibiotic)

A

Doryx, Minocin : bactericidal antibiotics, oral contraceptives AL,Ca,Mg,Zn,Fe
Minocin, Zmax: antacids

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15
Q

Antibacterial
contraindications
TetracyclineAntibiotic)
(Macrolide Antibiotic)

A

-impaired renal fxn
Minocin, Doryx : children under 8, pregnancy and lactation
Zmax: low K, Mg or bradycardia, arrhythmia

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16
Q

Antibacterial
TetracyclineAntibiotic)
(Macrolide Antibiotic)
adverse effects

A

Dizziness,Nausea, Diarrhea, abdominal pain
Minocin, Doryx: Vertigo, teeth discoloration
Doryx: sunlight sensitivity

17
Q

Antibacterial
PC
TetracyclineAntibiotic)
(Macrolide Antibiotic)

A

-empty stomach with full glass of water (Zmax formulations)
Minocin and Zmax: No antacids
Doryx: Monitor CBC

18
Q

Osteoporosis Agent

A

Alendrote Sodium
Raloxifene Hydrochloride

19
Q

Alendrote Sodium
Raloxifene Hydrochloride

A

Fosamax
Evista

20
Q

Osteoporosis Agent
Indications

A

Osteoporosis in post menopausal women
Evista : 60 mg (only women)
Fosamax : 10 mg
Fosamax : Bone problems in men

21
Q

Osteoporosis Agent
MOA

A

Evista : selective estrogen receptor modulator
Fosamax : inhibits osteoclast activity

22
Q

Osteoporosis Agent
Interactions
CAA

A

Fosamax : Ca, antacids,aspirin
Evista : NSAIDs, cholestyramine

23
Q

Osteoporosis Agent
Contraindication

A

Nursing mothers
Evista : Pregnancy
Fosamax : GI problems

24
Q

Osteoporosis Agent
Adverse effects

A

Fosamax : flatulence,osteonecrosis, musculoskelteal pain
Evista : hot flashes,sinustis,edema

25
Q

Osteoporosis
Agent
PC

A

swallow whole
Fosamax : dont lie down right after for 30
Monitor BMD
Evista : avoid not moving, take Ca and Vit D

26
Q

NSAIDs

A

Celecoxib
Ibuprofen
Naproxen
Meloxicam
Nabumetone
Diclofenac NA oral
Diclofenac NA topical

27
Q

Celecoxib
Ibuprofen
Naproxen
Meloxicam
Nabumetone
Diclofenac NA oral
Diclofenac NA topical

A

Celebrex
Motrin
Naprosyn
Mobic,Vivlodex,Anjeso
Relafen
Volteren & XR
Volteren gel

28
Q

NSAIDs indication

A

Arthritis
Celecoxib : 200mg (100,200,400)
Ibuprofen : 1200-3200( 400,600,100)
Naproxen : 250 to 500(250,375,500)
Meloxicam : 7.5(7.5,15)
Nabumetone : 500 to 2000( 550,750)
Diclofenac NA oral : 50,75,XR 100
Diclofenac NA topical: 2g up, 4g low
Painful periods
Celecoxib : 400
Ibuprofen : 500
Naproxen : 500

29
Q

NSAIDs MOA

A

COX inhibitor

30
Q

NSAIDs interactions

A

Aspirin,
Exception (Topical,Nabumetone) : Lithium

31
Q

NSAIDs Contraindication

A

Bleeding,thrombotic events

32
Q

NSAIDS adverse effects

A

Gastrointestinal problems
Exception (Celecoxib,oral ,meloxicam) : rash,pruritus
Celecoxib : sinutis, edema

33
Q

NSAIDs PC

A

Naproxen : empty stomach, no children
Nabumetone, Oral: alcohol
oral : swallow whole
topical : don’t shower after application 1 hour , nothing on it, sunlight exposure
Monitor
LFT and RFT
Naproxen : RFT
no monitor for topical