Drug Cards quiz 2 Flashcards
Hormone
Testerone Gel
Progesterone oral
Estrogens conjugated
Testosterone Gel
Progesterone oral
Estrogens conjugated
Androgel, Fortesta, Testim
Prometrium
Premarin
Hormone Indication
Testosterone :
deficiency/absence of testosterone
Progesterone:
-Prevention of endometrial hyperplasia in postmenopausal
-Secondary Amenorrhea
Estrogens:
–Vasomotor symtoms w/ menopause
-Female hypogonadism
-Female castration and primary ovarian failure
-Breast cancer
-Prostatic cancer
-Prostastic carcinoma
-Post menopausal osteoporosis
Hormone Doses
Testosterone Gel: 50 mg
Progesterone : 200 mg
Estrogen: 1.25 mg
Hormone MOA
-Testosterone:
Inhibit/stimulate mRNA transcription
-Progesterone: Increased synthesis of RNA
-Estrogen:stimulate specific RNA and protein synthesis @female sex organs
decrease FSH,LH,
Hormone
Interactions
Testosterone : insulin,corticosteroids
Progesterone : ketonazole
Estrogen : rifampin,hydratoins
Hormone
Contradiction
Testosterone :cancer, women, children, heart failure
Progesterone: cancer,peanut allergy, pregnancy, thrombophlebitis, liver dysfunction
Estrogen: breast cancer, neoplasia, pregnancy, genital bleeding ,nursing mothers
Hormone
Adverse effects
Testosterone :Increased PSA, emotional ,hypertension,Increased hemoglobin
Progesterone: abdominal pain, viral infection, cough,breast pain
Estrogen: alopecia ,hirsutism, abnormal menstrual bleeding, weight changes
Hormone
PC
Testosterone: No genital area,
Avoid showering
Monitor: hematocrit,hemoglobin,testosterone,psa,lipid panel,lft
Progesterone: caution when performing activities
Estrogen : discontinue if pregnant
Antibacterial
(TetracyclineAntibiotic)
(Macrolide Antibiotic)
Minocycline Hydrochloride
Doxycycline Hyclate
Azithromycin Dihydrate
Minocycline Hydrochloride
Azithromycin Dihydrate
Doxycycline Hyclate
Minocin, Dynacin,Solodyn ER
Zithromax, Zmax
Vibramycin, Doryx
Antibacterial
Indications
TetracyclineAntibiotic)
(Macrolide Antibiotic)
Syphilis, Gonorrhea, chlamydia/ureaplasma
Minocin : meningitidis
Doryx : Malaria
Exception
Zmax: otitis media, pneumonia, ,ulcer
Antibacterial
TetracyclineAntibiotic)
(Macrolide Antibiotic)
MOA
competitively binding to 30S ribosomal subunits in bacteria
Antibacterial
Interactions
TetracyclineAntibiotic)
(Macrolide Antibiotic)
Doryx, Minocin : bactericidal antibiotics, oral contraceptives AL,Ca,Mg,Zn,Fe
Minocin, Zmax: antacids
Antibacterial
contraindications
TetracyclineAntibiotic)
(Macrolide Antibiotic)
-impaired renal fxn
Minocin, Doryx : children under 8, pregnancy and lactation
Zmax: low K, Mg or bradycardia, arrhythmia