Drug card quiz 4 Flashcards
Diuretics
Butemide
Metalozone
Hydrochorothiazide
Furosemide
Chlorthalidone
Spironolactone
Triamterene
Torsemide
Hydrochorothiazide
Torsemide
Bumetanide
Chlorthalidone
Furosemide
Triamterene with Hydrochorothiazide
Spironolactone
Metolazone
Microzide (Diuretic)
Demadex (Diuretic)
Bumex (Diuretic)
Hygrotan
Lasix
Dayside, Maxzide (Diuretic)
Aldactone (Diuretic)
Diuretic Indications
Edema :
Hydrocholorothiazide 25 to 100 mg
Torsemide 5 to 10
Butemide 0.5 to 2 mg
Chorthalidone 50 mg
Furosemide 20 to 80 mg
Triamterene 37.5 t and 25 hydro/ 75 t and 50 hydro
Spinolactone 25 to 200 mg
Metolazone 5 to 25
Hypertension ( except Butemide)
Spinolactone ( Hypokalemia, Hyperaldosterone )
Diuretic MOA
inhibits reabsorption of Na
Triamterenr: Inhibits Na + in exchange for K
Spinolactone: Comp antagonist of aldosterone
Torsemide : Inhibit Na/K/Cl carrier system
Diuretic Contraindications
anuria
sensitive to sulfa drugs
gout,cirrhosis,diabetes,
impaired renal/hepatic fxn, - - taking ACTH (Hydrochrothiazide)
Diuretic adverse effects
-All diuretics except toresimide
Dry mouth, muscle cramps, nausea, anemia,
hypotension, anorexia, hyperglycemia, rash
- Butemide and Furosemide : hearing loss
- Butemide : hypochloremia, hyponatremia ,hypokalemia, hyperglycemia
- Toresimide excessive urination
- Impaired hearing (but amide,furosemide)
Diuretics PC
take w/ food or milk
avoid sun
take in the morning
Monitor
K : Hydrochoro, Torsemide, Triamterene,Metolazone, Furosemide, Butemide ( except spinolactone chlorthalidone)
BP: Hydrochoro
Na: Metolazone
BPH agent
Finasteride
Tamsulosin Hydrochloride
Alfuzosin Hydrochloride
Dutasteride
Tamsulosin Hydrochloride
Finasteride
Alfuzosin Hydrochloride
Dutasteride
Flomax (BPH Agent)
Proscar (BPH Agent)
Uroxatral (BPH Agent)
Avodart (Prostate anti-inflammatory)
BPH agent Indications
Benign prostatic hyperplasia
Proscar : 5mg
Flomax : 0.4 mg
Uroxatral : 10 mg
Avodart : 0.5 mg
BPH agent MOA
Block alpha adrenergic receptors
(alfuzosin,tamsulosin )
Comp inhibits 5-alpha-reductase (finasteride, Dustateride)
BPH contraindications
Women and Children (Finasteride,Dutasteride)
Hepatic Impairment Alfuzosin)
alpha adrenergic carcinoma Tamsulosin)
BPH adverse effects
Alfuzosin, Tamsulosin : floppy iris,priaprism Headache, fatigue, dizziness,
Tamsulosin: rhinitis,asthenia,sinustis
- Depression, erectile dysfuction, decreased libido,male infertility (Finasteride,Dutasteride)
BPH PC
Finasteride, Dustasteride: Pregnancy
Dustasteride : Men can’t donate blood
- Alfuzosin : take w/ food, same time everyday, don’t crush/chew, care w/ machinery
- Tamsulosin : take 30 min following meal, consult physician before stop
Monitor :
Alfuzosin : BP
Finasteride,Dutasteride : PSA
Anti arrhythmic
Amidrone
Sotalol HCL
