Drug card quiz 3 Flashcards
Urinary bladder modifier
Solifenacin Succinate
Oxybutynin Chloride
Tolterodine Tartrate
Solifenacin Succinate
Oxybutynin Chloride
Tolterodine Tartrate
Vesicare
Ditropan, Ditropan XL
Deltrol, Deltrol XR
Urinary bladder modifier
Dosage
Solifenacin Succinate
5 mg, 10 mg
Oxybutynin Chloride
Tablet : 5 mg, 10mg, 15 mg
Syrup : 5mg/ 5mL
(available in topical patch)
Tolteridone : 1 and 2
2,4
Urinary bladder modifier indications
- overactive bladder
Vesicare,ditropan =5mg
Detrol = 4
Urinary bladder modifier
MOA
Solifenacin, Tolterodone :
competitive muscarinic receptor antagonist
Oxybutynin Chloride :
inhibits muscarinic action of ACH on smooth muscle
Urinary bladder modifier
contraindications
- urinary retention
-gastric retention - uncontrolled narrow angle glaucoma
Detrol, Vesicare :
-nursing mothers
Urinary bladder modifier
adverse effects
dry mouth, constipation, blurred vision,dizziness
Solifinacin : UTI, abdominal pain
Urinary bladder modifier
PC
- avoid hot weather
- care operating heavy machinery/mental alertness
Oxybutinin, Solifenacin : - swallow whole
Tolteridone :
No alcohol
Cephalosporin
Sulfonamide Antiobiotics
Antibacterial
Cephalexin Monohydrate
Nitrofurantoin
Sulfamethoxazole w/ Trimethoprim
Cephalexin Monohydrate
Nitrofurantoin
Sulfamethoxazole w/ Trimethoprim
Keflex
Macrodantin, Macrobid, Furadantin
Bactrim, Septra
Antibacterial
dosage
Cephalexin :250 mg, 500mg , 750mg
powder
Nitrofuran : 25,50,100
suspension
Sulfamethoxazole : T80,S400
suspension, injection
250mg to 1 g every six hours
Antibacterial
indications
Nitrofuran, Cephalexin, Sulfamethoxazole:
UTI, bacterial infection
Sulfamethoxazole :
travelers diarrhea, pneumonities (PCP)
Antibacterial
MOA
Cephalexin : acylation of transpeptidase enzyme
Nitrofuran : inhibition of acetyl co-enzyme A
Sulfamethoxazole : inhibiting enzyme dihydrfolate reductase
Antibacterial
interactions
Keflex : oral contraceptives
false positive for tests
Macrobid : Mg
Bactrim : Cyclosporine
Antibacterial
contraindications
Impaired renal fxn
Septra, Keflex : sulfa drug allergy,
Septra, Macrodantin : pregnancy, infants,
Macrodantin : anuria,oliguria,
Keflex : penicillin,
Septra: magaloblastic anemia
Antibacterial
adverse effects
Nitrofuran, Cephalexin, Sulfomethoxazole : nausea , vomiting , diarrhea , hives, itching, rash
Sulfamethoxazole : stevens Johnsons syndrome, sunlight sensitivity
Antibacterial PC
Nitrofuran : urine discoloration
Cephalexin, Sulfomethoxazole : empty stomach 2 hours
Sulfamethoxazole : sunlight sensitivity
COPD
Ipratropium Bromide
Ipratropium Bromide w/ Albuterol Sulfate
Tiotropium Bromide