Droperidol

Question 1

Droperidol: Introduction

Answer 1

Droperidol is neuroleptic, antipsychotic agent that acts on alpha and dopamine receptors, resulting in sedation.

Use of a sedative agent should never be considered routine. Have a high threshold to offer or administer.

Question 2

Droperidol: Indication

Answer 2

1) DAB (RASS1-3) if considered appropriate, where risk to safety is evident and de-escalation has not been effective

2) Dementia and frail patients where olanzapine cannot be administered or is ineffective

Question 3

Droperidol: Contraindications

Answer 3

1) Known Allergy
2) Parkinson’s Disease
3) Where Ketamine has been administered to sedate this patient
4) Age <6 years
5) Post-ictal DAB

Question 4

Droperidol: Considerations

Answer 4

Extrapyramidal effects / Dyskinesia
Increased falls risk
Hypotension
Apply monitoring as soon as practicable

Question 5

Droperidol: Precautions

Answer 5

Address organic causes
Post ROSC agitation - consult CSP/ASMA
Dementia - apply caution, use lower dose