dopamine hypothesis and neurotransmitters

Question 1

what does the dopamine hypothesis suggest

Answer 1

that schizophrenia is a result of excess dopamine

Question 2

what is their an increase in to cuase symptoms

Answer 2

sensitivity an density

Question 3

where does this increase of sensitivity and density occour

Answer 3

at the synapses

Question 4

what does this increase in sensitivity lead to

Answer 4

increase activity of dopamine at the synapses

Question 5

what are schizophrenics more likely to pick up

Answer 5

dopamine

Question 6

schizophrenics have a higher number of what

Answer 6

d2 sites

Question 7

where does overstimulation happen

Answer 7

mesolimbic pathway

Question 8

what does too much dopamine in the mesolimbic pathway lead to

Answer 8

positive symptoms

Question 9

what leads to negative symptoms

Answer 9

too little dopamine in the mesocortiol pathway

Question 10

give supporting research for the dopamine hypothesis

Answer 10

carlsson et al
brain scanning shows that if those with schizophrenia are given amphetamines. greater relase of dopamine than those without schizophrenics took it.
t/f suggests those with schizophrenia more sensative to excess dopamine.

Question 11

give the name of anouther supporting research

Answer 11

wong et al

Question 12

what did Wong et al find

Answer 12

PET scans show greater density of dopamine receptors in unmedicated compared to medicated schizophrenics
t/f suggests that density of dopmaine receptors does contributr to increased activity and schizophrenic symptoms

Question 13

name one weakness of the dopamine hypothesis to explain schizophrenia

Answer 13

it is reductionist

Question 14

define the reductionist point

Answer 14

theory only considers the role of the neurotransmitter dopamine and these abnormalities have not been found in all schizophrenics. social and enviromental factors have been found to trigger schizophrenia and the role of neurotransmiiters does not account for this
t/f a biological explination does not account for nurture and so is not a holistic explination of schizophrenia

Question 15

give the name of supporting research that down plays schizophrenia

Answer 15

jackson

Question 16

explain jacksons supporting research

Answer 16

reviewd evidance from various studies found no consistant differences between level of dopamine in untreated schizophrenics and control group
t/f casting doubt on role of dopamine in development of schizophrenic symptoms

Question 17

what are the three neurotransmitters used to explain schizophrenia

Answer 17

dopamine
glutimate
seretonin

Question 18

what do low levels of glutimate corrispond to

Answer 18

high levels of dopamine

Question 19

why does this occour

Answer 19

because glutiate inhibits dopamine

Question 20

give one place glutimate failure occours

Answer 20

cerbral cortex

Question 21

what does glutimate failure in the cerbral cortex lead to

Answer 21

negative symptoms

Question 22

give an example of a negative symptom

Answer 22

inappropriate emotions

Question 23

give anouther place glutimate failure occours

Answer 23

basal gangalia

Question 24

what does failure in the basal ganglia lead to

Answer 24

positive symptoms

Question 25

give an example of a positive symptom

Answer 25

delusions

Question 26

what are high levels of serotonin linked to

Answer 26

positive symptoms

Question 27

what condition produces glutermate

Answer 27

hypoglutametergenic

Question 28

what is anouther supporting point

Answer 28

seeman

Question 29

what did seeman find

Answer 29

increased density of dopamine D2 receptors in postmortem brain of schizophrenia suffers

Question 30

what is anouther supporting research

Answer 30

amphetamine users research

Question 31

what does the role of amphetamines play in schizophrenia

Answer 31

showed that aphjetamine users had similar symptoms to schizophrenics becuase the drug causes an increase in dopamine