Dog genetic diseases

Question 1

CLAD

Answer 1

canine leukocyte adhesion deficiency
immunodeficiency - recurrent infections

Question 2

SCID

Answer 2

Severe Combined immunodeficiency
disturbed development of functional T cells and B cells due to genetic mutations

Question 3

haemostatic disorders

Answer 3

• *Haemophilia A and B**: something wrong with coag. factors
• *haemolytic anaemia:** haemolysis, springer spaniel
• *von willebrand:** VW is a factor required for platelet adhesion!

Question 4

metabolic diseases (lysosomal storage)

Answer 4

• *ceroid-lipofuscinosis:** pigments build up causing perm. Loss of motor and physiological ability
• *cystinuria**: cystein crystals in urine
• *mucopolysaccharidosis:** perm. cellular damage: mental, organs, abilities, appaerance

Question 5

Muscular dystrophy

Answer 5

in retrievers, weakening and breakdown of skeletal muscle

Question 6

Skeletal

Answer 6

• *chondroplasia** aka short leggedness, breed characteristic!
• *dwarfism:** yorkshire terrier and chihuahua have some dwarf genes in their gene pool

Question 7

cranial disorders

Answer 7

• *narcolepsy** - doberman, sleep reg.
• *deafness**: blue eyed white dogs (bull terrier)