DNA3

Question 1

Draw C’2 endo furanose

Answer 1

See slide 4 DNA3

Question 2

Draw C’2 exo furanose

Answer 2

see slide 4 DNA3

Question 3

In furanose puckering, what does the term endo mean and what does the term twist mean?

Answer 3

endo: when one carbon is lifted or lowered from the horizontal plane of the molecule
Twist: when one carbon is above and another adjacent carbon is below the horizontal plane of the molecule

Question 4

On the furanose pucker wheel, A-form DNA and RNA are ……

Answer 4

North

Question 5

On the furanose pucker wheel, B-form DNA and RNA are

Answer 5

South

Question 6

Furanose puckering is controlled by the …… …… ……

Answer 6

potential energy surface

Question 7

What three forces are in tension with phosphate-phosphate repulsions?

Answer 7

1. Furanose puckering
2. Base Pairing
3. Base Stacking

Question 8

All dsRNA is close to what type of nucleic acid structure?

Answer 8

A-type

Question 9

What is the propeller twist of DNA?

Answer 9

The position of nucleic acids out of plane

Question 10

What happens at the junction of A-form and B-form DNA?

Answer 10

a bend

Question 11

What is hybridization?

Answer 11

DNA forming duplexes