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Microbiology > DNA Viruses > Flashcards

DNA Viruses Flashcards

1
Q

Name DNA virus families

A 
HHPPPPA
Herpes
Hepadna
Pox
Parvo
Papilloma
Polyoma
Adeno
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2
Q

General characteristics of Herpes virus

A

Enveloped
DS
Linear

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3
Q

Organisms in Herpesvirus family

A 
HSV-1,2
VZV
EBV
CMV
HHV-6,7,8
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4
Q

Mode of transmission of HSV-1

A

Respiratory, saliva

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5
Q

C/F of HSV 1

A

Orofacial - gingivostomatitis, herpes labialis
Ocular - keratoconjunctivitis
Skin - herpetic whitlow (finger), eythema multiformae, eczema herpeticum
CNS - Temporal lobe encephalitis

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6
Q

HSV 1 is latent in

A

Trigeminal ganglia

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7
Q

Cytopathology of HSV

A

Tzanck preparation - multinucleated giant cells
Wright/giemsa stain
Inclusion bodies - Cowdry type A bodies

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8
Q

Isolation of HSV

A

McCoy cell line - rounding and ballooning of cells

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9
Q

Other methods of DX of HSV

A

Ag - direct IF
DNA detection - PCR
Ab - ELISA

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10
Q

Transmission of HSV2

A

Sexual, perinatal

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11
Q

C/F of HSV 2

A

Herpes genitalis
Neonatal herpes
Meningitis

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12
Q

HSV2 latent in

A

Sacral ganglia

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13
Q

Treatment of HSV

A

Acyclovir

Vancyclovir

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14
Q

Mechanism of replication of HSV

A

Rolling circle mechanism

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Microbiology (9 decks)

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